Published on in Vol 12 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/81673, first published .
AI- vs Human-Based Assessment of Medical Interview Transcripts in a Generative AI–Simulated Patient System: Cross-Sectional Validation Study

AI- vs Human-Based Assessment of Medical Interview Transcripts in a Generative AI–Simulated Patient System: Cross-Sectional Validation Study

AI- vs Human-Based Assessment of Medical Interview Transcripts in a Generative AI–Simulated Patient System: Cross-Sectional Validation Study

Hiromizu Takahashi   1 , MD, PhD ;   Kiyoshi Shikino   2 , MD, MHPE, PhD ;   Takeshi Kondo   3, 4 , MD, MHPE, PhD ;   Yuji Yamada   5 , MD, MPH, PhD ;   Yoshitaka Tomoda   6 , MD, PhD, FACP ;   Minoru Kishi   7 , MD, PhD ;   Yuki Aiyama   8 , MD ;   Sho Nagai   9 , RN, PHN, MSN ;   Akiko Enomoto   9 , RN, PHN, MSN ;   Yoshinori Tokushima   10 , MD, PhD ;   Takahiro Shinohara   11 , MD ;   Fumiaki Sano   1 , MD ;   Takeshi Matsuura   12 , MD ;   Rikiya Watanabe   13 , MD ;   Toshio Naito   1 , MD, PhD

1 Department of General Medicine, Faculty of Medicine, Juntendo University, Tokyo, Japan

2 Department of Community-Oriented Medical Education, Graduate School of Medicine, Chiba University, Chiba, Japan

3 Center for Postgraduate Clinical Training and Career Development, Nagoya University Hospital, Nagoya, Japan

4 The School of Health Professions Education, Maastricht University, Maastricht, The Netherlands

5 Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States

6 Department of General Internal Medicine, Itabashi Chuo Medical Center, Tokyo, Japan

7 Department of Internal Medicine, Nishiwaki Municipal Hospital, Hyogo, Japan

8 Anesthesiology and Critical Care Medicine, Tenri Hospital, Nara, Japan

9 Department of Nursing, School of Nursing, University of Human Environments, Aichi, Japan

10 Department of General Medicine, Saga University Hospital, Saga, Japan

11 Department of General Medicine, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan

12 Department of General Medicine, Bibai City Hospital, Hokkaido, Japan

13 Department of General Internal Medicine, Kita-Harima Medical Center, Hyogo, Japan

Corresponding Author:

  • Hiromizu Takahashi, MD, PhD
  • Department of General Medicine
  • Faculty of Medicine, Juntendo University
  • 3-1-3 Hongo, Bunkyo Tokyo, 1130033 Japan
  • Tokyo
  • Japan
  • Phone: 81 3-3813-3111
  • Email: hrtakaha@juntendo.ac.jp