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This paper is in the following e-collection/theme issue:

Virtual Patients (141) Depression and Mood Disorders; Suicide Prevention (2507) Technology in Psychiatry/Clinical Psychology Training and Education (100) Anxiety and Stress Disorders (1640) Chatbots and Conversational Agents (1206) Health Professionals' Training in eHealth, Digital Medicine, Medical Informatics (297) Artificial Intelligence (AI) in Medical Education (818) Generative Language Models Including ChatGPT (1594)

Published on in Vol 11 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/68056, first published .
Woman on video call with doctor discussing health concerns

Leveraging Large Language Models for Simulated Psychotherapy Client Interactions: Development and Usability Study of Client101

Leveraging Large Language Models for Simulated Psychotherapy Client Interactions: Development and Usability Study of Client101

Authors of this article:

Daniel Cabrera Lozoya1 Author Orcid Image ;   Mike Conway1 Author Orcid Image ;   Edoardo Sebastiano De Duro2 Author Orcid Image ;   Simon D'Alfonso1 Author Orcid Image
Article Authors Cited by (16) Tweetations Metrics

Journals

  1. Schmidt S, Cabrera Lozoya D, Kiropoulos L, Conway M, D’Alfonso S. Psychology student and mental health practitioner experiences of and perspectives on Client101, a virtual client chatbot training tool. BMC Medical Education 2025;25(1) View
  2. Chen Y, Gao Y, Yu S, Zhao C, Lu Y. Large Language Models in Mental Health: A Systematic Review of Applications, Innovations and Ethical Challenges. Journal of Industrial Integration and Management 2026:1 View
  3. Yang J, Liu T, Luo Y, Niu T, Pang P, Xiang A, Yang Q. Exploring the application boundaries of LLMs in mental health: a systematic scoping review. Frontiers in Psychology 2026;16 View
  4. Kuczynski A, Areán P. Ensuring Optimal Engagement with AI Chatbots for Mental Health: Lessons Learned from Digital Mental Health Interventions. Current Treatment Options in Psychiatry 2026;13(1) View
  5. Soma C, Kuo P, Mehta M, Srikumar V, Imel Z, Atkins D. Artificial Intelligence to Support Human-Provided Mental Health Treatment. Annual Review of Clinical Psychology 2026;22(1):505 View
  6. Taguchi K. Current trends and prospects of AI-assisted cognitive behavioral therapy: from the perspective of support and complementation. Stress Science Research 2026;39(0):16 View
  7. Cavalera C, Frisone F, Rossi C, Oasi O, Pagnini F, Riva G, Antichi L. The Digital Mirror: Clinical Potentials and Relational Risks of Generative AI in Mental Health Interventions. Current Psychiatry Reports 2026;28(1) View
  8. De Lira P, Dias L, Queiroz J. A SUBSTITUIÇÃO DO PSICÓLOGO POR SISTEMAS DE INTELIGÊNCIA ARTIFICIAL: LIMITES ÉTICOS, CLÍNICOS E PROFISSIONAIS DA "TERAPIA POR IA". Revista de Geopolítica 2026;17(7):e2740 View
  9. Ha T, Han I, Yang H, Lee S. Using ChatGPT as a virtual client in counseling training: counselors‑in‑training’s perceptions across counseling self‑efficacy levels. Asia Pacific Education Review 2026 View
  10. Schuster R, Plessen C, Carlbring P, Walther A. AI Agents Are Coming: 5-Stage Taxonomy of Language-Based AI Systems for Psychiatry, Psychotherapy, and Counseling. JMIR Mental Health 2026;13:e91746 View
  11. Walther M, Taubner S, Gertz M. Multimodale Sprachmodelle in der psychotherapeutischen Aus- und Weiterbildung. Die Psychotherapie 2026;71(5):366 View
  12. Bossio Botero V, Yadav V, Ouyang J, Abbas A, Worthington M. A Voice-Enabled Virtual Patient System for Interactive Training in Standardized Clinical Assessment (Preprint). Journal of Medical Internet Research 2025 View
  13. Hu H, Zhou Y, Wang Q, Zou Y, Ma C, Si J, Liu J, Yu Z, Cui L, Ma F, Tian Q. From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Health. IEEE Transactions on Affective Computing 2026;17(3):2525 View
  14. Jafri F, Elsener M, Pulido K, Kumar A, Kardong-Edgren S, Edwards R. Implementation of Artificial Intelligence–Powered Patient Simulation for Communication Training in a Telehealth Transitional Care Program. Simulation in Healthcare: The Journal of the Society for Simulation in Healthcare 2026 View

Books/Policy Documents

  1. Warnett U, Sureephong P, Chernbumroong S, Duangnamol T. Information Retrieval and Knowledge Management. View

Conference Proceedings

  1. Kim H, Lee J, Oh H. Proceedings of the 41st ACM/SIGAPP Symposium on Applied Computing. EEG-Informed Neuroadaptive Language Model for CBT View