Innovations and Technology for Cancer Prevention and Screening

The Cost-Effectiveness of AI-Assisted Colonoscopy as a Primary or Secondary Screening Test in a Population-Based Colorectal Cancer Screening Program: Markov Modeling–Based Cost Effectiveness Analysis

Martin CS Wong, Junjie Huang, Thomas YT Lam, Louis HS Lau, Philip WY Chiu

J Med Internet Res 2025 (Sep 26); 27:e67762

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Bridging Technology and Pretest Genetic Services: Quantitative Study of Chatbot Interaction Patterns, User Characteristics, and Genetic Testing Decisions

Yang Yi, Lauren Kaiser-Jackson, Jemar R Bather, Melody S Goodman, Daniel Chavez-Yenter, Richard L Bradshaw, Rachelle Lorenz Chambers, Whitney F Espinel, Rachel Hess, Devin M Mann, Rachel Monahan, David W Wetter, Ophira Ginsburg, Meenakshi Sigireddi, Kensaku Kawamoto, Guilherme Del Fiol, Saundra S Buys, Kimberly A Kaphingst

J Med Internet Res 2025 (Sep 17); 27:e73391

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Identifying Predictors of Cervical Cancer Screening Uptake in Sub-Saharan Africa Using Machine Learning: Cross-Sectional Study

Nebebe Demis Baykemagn, Mekuriaw Nibret Aweke, Amare Mesfin, Lemlem Daniel Baffa, Muluken Chanie Agimas, Habtamu Wagnew Abuhay, Dagnew Getnet Adugna, Tewodros Getaneh Alemu, Alemu Teshale Bicha, Gebrie Getu Alemu

JMIR Public Health Surveill 2025 (Sep 17); 11:e71677

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Virtual Health Assistants in Preventive Cancer Care Communication: Systematic Review

Aantaki Raisa, Xiaobei Chen, Emma G Bryan, Carma L Bylund, Jordan M Alpert, Benjamin Lok, Carla L Fisher, Lyndsey Thomas, Janice L Krieger

JMIR Cancer 2025 (Sep 15); 11:e73616

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Trade-Off Analysis of Classical Machine Learning and Deep Learning Models for Robust Brain Tumor Detection: Benchmark Study

Yuting Tian

JMIR AI 2025 (Sep 15); 4:e76344

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Exploring Women’s Perceptions of Traditional Mammography and the Concept of AI-Driven Thermography to Improve the Breast Cancer Screening Journey: Mixed Methods Study

Kristýna Sirka Kacafírková, Anneleen Poll, An Jacobs, Antonella Cardone, Juan-Jose Ventura

JMIR Cancer 2025 (Sep 10); 11:e64954

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An eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Patients With Metastatic Cancers: Protocol for a Randomized Trial

Kimberley T Lee, Briana McLeod, Brian Egleston, Sarah Brown, Sarah Howe, Dominique Fetzer, Lauren Gutstein, Cara Cacioppo, Dana Clark, Susan M Domchek, Jessica Ebrahimzadeh, Dana Falcone, Demetrios Ofidis, Hannah Griffin, Rajia Mim, Santina Hernandez, Linda Fleisher, Kelsey Karpink, Enida Selmani, Aysha Tahsin, Lynne Wagner, Michelle Weinberg, Kuang Yi-Wen, Elisabeth Wood, Angela R Bradbury

JMIR Res Protoc 2025 (Aug 25); 14:e72515

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Deep Learning for the Early Detection of Invasive Ductal Carcinoma in Histopathological Images: Convolutional Neural Network Approach With Transfer Learning

Naga Shreya Chilumukuru, Pragya Priyadarshini, Yawo Ezunkpe

JMIR Form Res 2025 (Aug 21); 9:e62996

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Implementation of Clinical Practice Guidelines to Prevent Cervical Cancer: Mixed Methods Study

Oliver C Ezechi, Folahanmi T Akinsolu, Olunike R Abodunrin, Oluwabukola M Ola, Chisom Obi-Jeff, Ishak K Lawal, George U Eleje, Joseph D Tucker, Juliet I Iwelunmor

JMIR Cancer 2025 (Aug 15); 11:e68572

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Framework for Race-Specific Prostate Cancer Detection Using Machine Learning Through Gene Expression Data: Feature Selection Optimization Approach

David Agustriawan, Adithama Mulia, Marlinda Vasty Overbeek, Vincent Kurniawan, Jheno Syechlo, Moeljono Widjaja, Muhammad Imran Ahmad

JMIR Bioinform Biotech 2025 (Jul 31); 6:e72423

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Automating Colon Polyp Classification in Digital Pathology by Evaluation of a “Machine Learning as a Service” AI Model: Algorithm Development and Validation Study

David Beyer, Evan Delancey, Logan McLeod

JMIR Form Res 2025 (Jul 31); 9:e67457

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Optimizing Thyroid Nodule Management With Artificial Intelligence: Multicenter Retrospective Study on Reducing Unnecessary Fine Needle Aspirations

Jia-Hui Ni, Yun-Yun Liu, Chao Chen, Yi-Lei Shi, Xing Zhao, Xiao-Long Li, Bei-Bei Ye, Jing-Liang Hu, Li-Chao Mou, Li-Ping Sun, Hui-Jun Fu, Xiao-Xiang Zhu, Yi-Feng Zhang, Lehang Guo, Hui-Xiong Xu

JMIR Med Inform 2025 (Jul 30); 13:e71740

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Design and Validation of a Chatbot-Based Cervical Cancer Screening Decision Aid for Women Experiencing Socioeconomic Disadvantage: User-Centered Approach Study

Alice Le Bonniec, Catherine Sauvaget, Eric Lucas, Abdelhak Nassiri, Farida Selmouni

JMIR Cancer 2025 (Jul 24); 11:e70251

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The Cost-Effectiveness of Adding Helicobacter Pylori Screening to the National Gastric Cancer Screening Program in Korea: Protocol for a Cost-Effectiveness Modeling Study

Seowoo Bae, Joon Sung Kim, Moon Won Lee, Gwang Ha Kim, Young-Il Kim, Woon Tae Jung, Gwang Ho Baik, Beom Jin Kim, Joongyub Lee, Mina Suh, Jae Gyu Kim

JMIR Res Protoc 2025 (Jul 15); 14:e72228

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Co-Design of a Health Screening Program Fact Sheet by People Experiencing Homelessness and ChatGPT: Focus Group Study

Nóra Radó, Orsolya Németh, Sándor Békási

JMIR Form Res 2025 (Jul 04); 9:e68316

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Clinical Prediction Models Incorporating Blood Test Trend for Cancer Detection: Systematic Review, Meta-Analysis, and Critical Appraisal

Pradeep S Virdee, Kiana K Collins, Claire Friedemann Smith, Xin Yang, Sufen Zhu, Nia Roberts, Jason L Oke, Clare Bankhead, Rafael Perera, FD Richard Hobbs, Brian D Nicholson

JMIR Cancer 2025 (Jun 27); 11:e70275

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Using a Multilingual AI Care Agent to Reduce Disparities in Colorectal Cancer Screening for Higher Fecal Immunochemical Test Adoption Among Spanish-Speaking Patients: Retrospective Analysis

Meenesh Bhimani, R Hal Baker, Markel Sanz Ausin, Gerald Meixiong, Rae Lasko, Mariska Raglow-Defranco, Alex Miller, Subhabrata Mukherjee, Saad Godil, Anderson Cook, Jonathan D Agnew, Ashish Atreja

J Med Internet Res 2025 (Jun 25); 27:e71211

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Predicting Early-Onset Colorectal Cancer in Individuals Below Screening Age Using Machine Learning and Real-World Data: Case Control Study

Chengkun Sun, Erin Mobley, Michael Quillen, Max Parker, Meghan Daly, Rui Wang, Isabela Visintin, Ziad Awad, Jennifer Fishe, Alexander Parker, Thomas George, Jiang Bian, Jie Xu

JMIR Cancer 2025 (Jun 19); 11:e64506

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Implementation of a Quality Improvement and Clinical Decision Support Tool for Cancer Diagnosis in Primary Care: Process Evaluation

Sophie Chima, Barbara Hunter, Javiera Martinez-Gutierrez, Natalie Lumsden, Craig Nelson, Dougie Boyle, Kaleswari Somasundaram, Jo-Anne Manski-Nankervis, Jon Emery

JMIR Cancer 2025 (Jun 12); 11:e65461

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Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: Prompt Engineering Project

Emma Coen, Guilherme Del Fiol, Kimberly A Kaphingst, Emerson Borsato, Jackilen Shannon, Hadley Smith, Aaron Masino, Caitlin G Allen

JMIR Cancer 2025 (Jun 10); 11:e65848

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