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Risk Stratification in Immunoglobulin A Nephropathy Using Network Biomarkers: Development and Validation Study

Risk Stratification in Immunoglobulin A Nephropathy Using Network Biomarkers: Development and Validation Study

Recently, a Japanese cohort led by Koike et al [15] proposed the renal function–renal histology grading (RF-RG) stratification scheme for Ig AN, primarily referencing the clinical grade (proteinuria and e GFR) and histological lesions to predict renal failure risk accurately, making it clinically promising due to its simplicity.

Jiaxing Tan, Rongxin Yang, Liyin Xiao, Lingqiu Dong, Zhengxia Zhong, Ling Zhou, Wei Qin

J Med Internet Res 2025;27:e65563

Time Series AI Model for Acute Kidney Injury Detection Based on a Multicenter Distributed Research Network: Development and Verification Study

Time Series AI Model for Acute Kidney Injury Detection Based on a Multicenter Distributed Research Network: Development and Verification Study

Reference 2: Race and mortality after acute renal failure Reference 3: The effect of specialized continuous renal replacement therapy team in acute kidney injury Reference 8: Electronic health records accurately predict renal replacement therapy in acute kidney injury Reference 25: Acute renal failure - definition, outcome measures, animal models, fluid therapy and information Adverse effects of nonsteroidal antiinflammatory drugs: an update of gastrointestinal, cardiovascular and renalrenal

Suncheol Heo, Eun-Ae Kang, Jae Yong Yu, Hae Reong Kim, Suehyun Lee, Kwangsoo Kim, Yul Hwangbo, Rae Woong Park, Hyunah Shin, Kyeongmin Ryu, Chungsoo Kim, Hyojung Jung, Yebin Chegal, Jae-Hyun Lee, Yu Rang Park

JMIR Med Inform 2024;12:e47693

Effects of Empagliflozin in Type 2 Diabetes With and Without Chronic Kidney Disease and Nondiabetic Chronic Kidney Disease: Protocol for 3 Crossover Randomized Controlled Trials (SiRENA Project)

Effects of Empagliflozin in Type 2 Diabetes With and Without Chronic Kidney Disease and Nondiabetic Chronic Kidney Disease: Protocol for 3 Crossover Randomized Controlled Trials (SiRENA Project)

Increased renal reabsorption of sodium and glucose mediated by the SGLT2 channels is thought to be an important pathophysiological feature of diabetic nephropathy, instigating an increase in renal blood flow (RBF) via tubule-glomerular feedback mechanisms [16]. This, in turn, causes renal hyperfiltration; intraglomerular hypertension; and in time, kidney damage.

Steffen Flindt Nielsen, Camilla Lundgreen Duus, Niels Henrik Buus, Jesper Nørgaard Bech, Frank Holden Mose

JMIR Res Protoc 2024;13:e56067

The Role of Metabolic Dysfunction–Associated Fatty Liver Disease in Developing Chronic Kidney Disease: Longitudinal Cohort Study

The Role of Metabolic Dysfunction–Associated Fatty Liver Disease in Developing Chronic Kidney Disease: Longitudinal Cohort Study

CKD can develop into end-stage renal disease, which can be fatal if renal replacement therapy is not an option [2]. The prevalence of CKD is 10.8% in China [3]. Therefore, it is of great public health importance to explore the related risk factors of CKD and take active preventive measures. Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis without excessive alcohol consumption or other competing factors and fat accumulation in more than 5% of hepatocytes [4].

Suosu Wei, Jian Song, Yujie Xie, Junzhang Huang, Jianrong Yang

JMIR Public Health Surveill 2023;9:e45050

Clinical Utility of the OmniGraf Biomarker Panel in the Care of Kidney Transplant Recipients (CLARITY): Protocol for a Prospective, Multisite Observational Study

Clinical Utility of the OmniGraf Biomarker Panel in the Care of Kidney Transplant Recipients (CLARITY): Protocol for a Prospective, Multisite Observational Study

Therefore, the aim of this study is to evaluate change in renal function over time in kidney transplant recipients who are undergoing Omni Graf monitoring in conjunction with patients’ medication-related symptom burden (MRSB) monitoring. CLARITY is a 3-year prospective, multisite, observational study of 2000 participants with a matched control, measuring the impact of real-time patients’ MRSB and the Omni Graf biomarker panel on change in renal function over time.

James N Fleming, Timothy Cober, Janelle Hickey, Leslie Stach, Allison Kawano, Amanda Szczepanik, Alicia Watson, Yuka Imamura, Juston Weems, Patricia West-Thielke

JMIR Res Protoc 2022;11(12):e41020

Use of Telemedicine in Pediatric Services for 4 Representative Clinical Conditions: Scoping Review

Use of Telemedicine in Pediatric Services for 4 Representative Clinical Conditions: Scoping Review

Include: Children (0-18 years) receiving outpatient care for any of the following: diabetes, asthma, epilepsy, or renal disease Interventions: telemedicine, remote consultation, video call, remote patient monitoring (collecting patient data outside of traditional health care settings to support ongoing patient care) Studies comparing interventions with usual outpatient care (including control arms, historic comparisons, or based on user with or without clinician perceptions) Studies published between 2011 and

Genevieve Southgate, Arrash A Yassaee, Matthew J Harmer, Helen Livesey, Kate Pryde, Damian Roland

J Med Internet Res 2022;24(10):e38267

Usability Testing of the Kidney Score Platform to Enhance Communication About Kidney Disease in Primary Care Settings: Qualitative Think-Aloud Study

Usability Testing of the Kidney Score Platform to Enhance Communication About Kidney Disease in Primary Care Settings: Qualitative Think-Aloud Study

CKD makes me feel better than end stage renal failure, so that makes me feel empowered because I'm at risk for chronic kidney disease, which is not end stage renal failure. The Kidney Score Platform is an online educational tool that was developed to promote communication and discussion about kidney disease among patients and their primary care clinicians. Usability findings demonstrate that this goal was met, with the majority of patients finding the digital tool to be helpful and easy to navigate.

Delphine S Tuot, Susan T Crowley, Lois A Katz, Joseph Leung, Delly K Alcantara-Cadillo, Christopher Ruser, Elizabeth Talbot-Montgomery, Joseph A Vassalotti

JMIR Form Res 2022;6(9):e40001

Hemodialysis Record Sharing: Solution for Work Burden Reduction and Disaster Preparedness

Hemodialysis Record Sharing: Solution for Work Burden Reduction and Disaster Preparedness

Patients undergoing hemodialysis (HD) require collaborative team care, not only because their renal function is poor but also because they are vulnerable to various comorbidities [1,2]. Since an increase in the number of comorbidities makes care for patients more complex, multiple medical facilities may need to share patient information, and diverse specialist expertise may be required for patient management.

Keisuke Ido, Mariko Miyazaki, Masaharu Nakayama

JMIR Form Res 2022;6(7):e32925

Sodium-Glucose Cotransporter-2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Combination Therapy in Type 2 Diabetes: Protocol for a Kidney End Points Real-world Study (COMBi-KID Study)

Sodium-Glucose Cotransporter-2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Combination Therapy in Type 2 Diabetes: Protocol for a Kidney End Points Real-world Study (COMBi-KID Study)

Diabetes continues to be the leading cause of chronic kidney disease (CKD) and end-stage kidney disease (ESKD) requiring renal replacement therapy. Overall, about 40% of people with type 2 diabetes have evidence of diabetic kidney disease (DKD) [1-4].

Michael Feher, William Hinton, Anna Forbes, Neil Munro, Mark Joy, David Wheeler, Simon de Lusignan

JMIR Res Protoc 2022;11(7):e34206