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Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: Prompt Engineering Project

Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: Prompt Engineering Project

Prior results from the BRIDGE (Broadening the Reach, Impact, and Delivery of Genetic Services) trial showed equivalence between a technology-based chatbot approach and standard of care in the completion of pretest genetics education and completion of genetic testing among unaffected primary care patients meeting criteria for cancer genetic evaluation [20].

Emma Coen, Guilherme Del Fiol, Kimberly A Kaphingst, Emerson Borsato, Jackilen Shannon, Hadley Smith, Aaron Masino, Caitlin G Allen

JMIR Cancer 2025;11:e65848

Cardiac Repair and Regeneration via Advanced Technology: Narrative Literature Review

Cardiac Repair and Regeneration via Advanced Technology: Narrative Literature Review

Combined AI models will address highly complicated cardiovascular clinical genetics [65]. AI profoundly apprehends complex patterns in imaging profiles and offers quantitative assessments of radiographic properties, serving as a valuable tool for enhancing imaging postprocessing. For instance, a combined convolutional neural network and recurrent neural network has achieved enhanced accuracy in predicting stenosis (≥50%) upon examining genetic variables grouped into training and testing samples [32,66].

Yugyung Lee, Sushil Shelke, Chi Lee

JMIR Biomed Eng 2025;10:e65366

Exploring Molecular Genetics Research on Obesity in Malaysia: Protocol for a Scoping Review

Exploring Molecular Genetics Research on Obesity in Malaysia: Protocol for a Scoping Review

Additionally, genetic variants linked to abdominal obesity have been found to predict waist circumference regain after weight loss, emphasizing the role of genetics in long-term weight management [27]. Studies such as the OBEGEN study underscore the importance of integrating genetic testing with clinical data to enhance the predictability of weight loss outcomes following bariatric surgery [28]. These findings are corroborated by subsequent research [29,30].

Liyana Ahmad Zamri, Norhashimah Abu Seman, Nur Azlin Zainal Abidin, Siti Sarah Hamzah

JMIR Res Protoc 2024;13:e60838

Improving Social Media-Based Support Groups for the Rare Disease Community: Interview Study With Patients and Parents of Children with Rare and Undiagnosed Diseases

Improving Social Media-Based Support Groups for the Rare Disease Community: Interview Study With Patients and Parents of Children with Rare and Undiagnosed Diseases

Candidates were identified by genetics specialists using convenience sampling, and those individuals who expressed verbal interest in participation were scheduled for a 1-time phone interview. The recruitment strategy was agnostic as to whether candidates were intensive or casual users of social media, and even individuals who preferred not to use DRSGs at all were invited to participate.

Tom A Doyle, Samantha L Vershaw, Erin Conboy, Colin M E Halverson

JMIR Hum Factors 2024;11:e57833