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Understanding the Relationship Between Ecological Momentary Assessment Methods, Sensed Behavior, and Responsiveness: Cross-Study Analysis

Understanding the Relationship Between Ecological Momentary Assessment Methods, Sensed Behavior, and Responsiveness: Cross-Study Analysis

The findings from this study will inform refinements in EMA methodology and guide future research to improve the reliability of EMA-derived data and the effectiveness of just-in-time interventions. In-the-moment sampling builds a foundation for designing effective just-in-time interventions [14]. Mc Devitt-Murphy et al [15] used such a technique to combat anxiety by prompting individuals to write about their worries and initiate physical activity.

Diane Cook, Aiden Walker, Bryan Minor, Catherine Luna, Sarah Tomaszewski Farias, Lisa Wiese, Raven Weaver, Maureen Schmitter-Edgecombe

JMIR Mhealth Uhealth 2025;13:e57018

Evaluating the Effectiveness of Large Language Models in Providing Patient Education for Chinese Patients With Ocular Myasthenia Gravis: Mixed Methods Study

Evaluating the Effectiveness of Large Language Models in Providing Patient Education for Chinese Patients With Ocular Myasthenia Gravis: Mixed Methods Study

Unlike previous research, which primarily focused on English-language medical Q and A, this study is the first to assess the educational effectiveness of LLMs for Chinese patients with OMG. Moreover, while most previous studies evaluated AI-generated responses from an expert perspective, our study uniquely integrates real patient interactions with chatbots, enabling a more practical and patient-centered assessment of LLM effectiveness.

Bin Wei, Lili Yao, Xin Hu, Yuxiang Hu, Jie Rao, Yu Ji, Zhuoer Dong, Yichong Duan, Xiaorong Wu

J Med Internet Res 2025;27:e67883

Identification of Patients With Congestive Heart Failure From the Electronic Health Records of Two Hospitals: Retrospective Study

Identification of Patients With Congestive Heart Failure From the Electronic Health Records of Two Hospitals: Retrospective Study

Some applications of these models in inpatient fall detection [14], emergency triage notes [15], and inpatient fall risk assessment [16] have already achieved a high level of effectiveness using a variety of modeling methods, including large language models such as Bidirectional Encoder Representations from Transformers, showing the need for further development in other medical applications.

Daniel Sumsion, Elijah Davis, Marta Fernandes, Ruoqi Wei, Rebecca Milde, Jet Malou Veltink, Wan-Yee Kong, Yiwen Xiong, Samvrit Rao, Tara Westover, Lydia Petersen, Niels Turley, Arjun Singh, Stephanie Buss, Shibani Mukerji, Sahar Zafar, Sudeshna Das, Valdery Moura Junior, Manohar Ghanta, Aditya Gupta, Jennifer Kim, Katie Stone, Emmanuel Mignot, Dennis Hwang, Lynn Marie Trotti, Gari D Clifford, Umakanth Katwa, Robert Thomas, M Brandon Westover, Haoqi Sun

JMIR Med Inform 2025;13:e64113

Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map

Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map

Together, results to date indicate that XR holds great promise for supporting biopsychosocial treatment for pain management for youth and adults; however, consistency in measurement as well as defined outcomes for assessing the effectiveness of XR research are missing, thereby limiting the ability to coordinate research efforts and examine effectiveness on a large scale.

Courtney W Hess, Brittany N Rosenbloom, Giulia Mesaroli, Cristal Lopez, Nhat Ngo, Estreya Cohen, Carley Ouellette, Jeffrey I Gold, Deirdre Logan, Laura E Simons, Jennifer N Stinson

JMIR Pediatr Parent 2025;8:e63854

Exploring Engagement With and Effectiveness of Digital Mental Health Interventions in Young People of Different Ethnicities: Systematic Review

Exploring Engagement With and Effectiveness of Digital Mental Health Interventions in Young People of Different Ethnicities: Systematic Review

Table 1 contains detailed data on the 7 included studies regarding demographics, sample sizes, digital interventions used, and the outcomes measured that were relevant to our research question (measures of user engagement and effectiveness of the DMHI). Three studies primarily examined engagement [19-21], while 3 others addressed effectiveness [22-24], and 1 study [25] explored both engagement and effectiveness.

Rinad Bakhti, Harmani Daler, Hephzibah Ogunro, Steven Hope, Dougal Hargreaves, Dasha Nicholls

J Med Internet Res 2025;27:e68544

Evaluation of an Online-Based Self-Help Program for Patients With Panic Disorder: Randomized Controlled Trial

Evaluation of an Online-Based Self-Help Program for Patients With Panic Disorder: Randomized Controlled Trial

A systematic review and meta-analysis including 27 studies on i CBT for panic disorder [25] showed high efficacy and effectiveness for reducing symptoms of panic disorder (hedges g=1.16) and agoraphobia (hedges g=0.91) compared with waitlist.

Christopher Lalk, Teresa Väth, Sofie Hanraths, Luise Pruessner, Christina Timm, Steffen Hartmann, Sven Barnow, Julian Rubel

J Med Internet Res 2025;27:e54062

Effectiveness of the Safe Step Digital Exercise Program to Prevent Falls in Older Community-Dwelling Adults: Randomized Controlled Trial

Effectiveness of the Safe Step Digital Exercise Program to Prevent Falls in Older Community-Dwelling Adults: Randomized Controlled Trial

The primary aim of this randomized controlled trial was to evaluate the effectiveness of the Safe Step app in reducing fall rates and fall risk over a 1-year intervention period. Additional aims were to describe fall-related injuries in both the exercise and control groups, study attrition, and adherence to the Safe Step exercise program.

Beatrice Pettersson, Lillemor Lundin-Olsson, Dawn A Skelton, Per Liv, Magnus Zingmark, Erik Rosendahl, Marlene Sandlund

J Med Internet Res 2025;27:e67539

Digital Health Intervention Effect on Older Adults With Chronic Diseases Living Alone: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Digital Health Intervention Effect on Older Adults With Chronic Diseases Living Alone: Systematic Review and Meta-Analysis of Randomized Controlled Trials

For adults with type 2 diabetes mellitus, Aminuddin et al [20] examined the effectiveness of a smartphone app on self-efficacy, self-management activities, health-related quality of life, glycated hemoglobin, BMI, and blood pressure levels, finding that it led to improvements in health behaviors and enhanced the effectiveness of self-management activities [20].

Yoonseo Park, Eun-Ji Kim, Sewon Park, Munjae Lee

J Med Internet Res 2025;27:e63168

Glucagon-Like Peptide-1 Receptor Agonists Combined With Personalized Digital Health Care for the Treatment of Metabolic Syndrome in Adults With Obesity: Retrospective Observational Study

Glucagon-Like Peptide-1 Receptor Agonists Combined With Personalized Digital Health Care for the Treatment of Metabolic Syndrome in Adults With Obesity: Retrospective Observational Study

Therefore, the aim of this study is to measure the effectiveness of GLP-1 and GLP-1/gastric inhibitory polypeptide (GIP) medications when combined with a continuous, digitally delivered behavioral change model involving a multidisciplinary team in the treatment of Met S components and weight among individuals with obesity in the UAE population. Zone.Health, introduced by meta[bolic] [12] in 2023, is a value-based 6-month weight loss program designed to be used in combination with pharmacotherapy.

Hala Zakaria, Hadoun Jabri, Sheikha Alshehhi, Milena Caccelli, Joelle Debs, Yousef Said, Joudy Kattan, Noah Almarzooqi, Ali Hashemi, Ihsan Almarzooqi

Interact J Med Res 2025;14:e63079

Acceptability and Effectiveness of a Fully Web-Based Nutrition and Exercise Program for Individuals With Chronic Disease During COVID-19: Randomized Controlled Trial

Acceptability and Effectiveness of a Fully Web-Based Nutrition and Exercise Program for Individuals With Chronic Disease During COVID-19: Randomized Controlled Trial

Our primary effectiveness outcome was the change in LEFS score from baseline to 12 weeks between the control and combined intervention arms. Secondary objective effectiveness outcomes included the 12-week change in objective physical function comparing the control and intervention groups for the 2-minute step test, chair sit-to-stand (30 and 60 seconds), plank, shoulder range of movement, and 1-legged balance.

Puneeta Tandon, Kathleen P Ismond, Graeme Purdy, Christofer Cruz, Evelyn Etruw, Kirsten Suderman, Ashley Hyde, Michael Stickland, John C Spence, Dale C Lien, Rahima Bhanji, Carla M Prado, Antonio Miguel-Cruz, Anil A Joy, Maryna Yaskina, Margaret L McNeely

J Med Internet Res 2025;27:e57537