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Potential Harms of Feedback After Web-Based Depression Screening: Secondary Analysis of Negative Effects in the Randomized Controlled DISCOVER Trial

Potential Harms of Feedback After Web-Based Depression Screening: Secondary Analysis of Negative Effects in the Randomized Controlled DISCOVER Trial

In the last decades, depression screening has been increasingly discussed as promising to reach those affected but undetected at an early stage. In addition to population-level screening in routine clinical care, as, for example, recommended in the United States [3], advocates also speak out in favor of screening for depression on the web [4]. For many affected individuals, the web is already the favored source for information on mental health [5,6].

Franziska Sikorski, Bernd Löwe, Anne Daubmann, Sebastian Kohlmann

J Med Internet Res 2025;27:e59476

Mobile Health Interventions for Modifying Indigenous Maternal and Child–Health Related Behaviors: Systematic Review

Mobile Health Interventions for Modifying Indigenous Maternal and Child–Health Related Behaviors: Systematic Review

The literature screening was performed using the Covidence systematic review software. After removing duplicate articles, the title and the abstract screen were performed by 1 reviewer per article (SI, OE, and AD). The studies selected for full-text review were screened by 2 independent assessors (SI, OE, and AD) against the eligibility criteria, with conflicts managed with discussion and with the assistance of an expert reviewer (BB).

Sana Ishaque, Ola Ela, Anna Dowling, Chris Rissel, Karla Canuto, Kerry Hall, Niranjan Bidargaddi, Annette Briley, Claire T Roberts, Billie Bonevski

J Med Internet Res 2025;27:e57019

Vital Sign and Biochemical Data Collection Using Non-contact Photoplethysmography and the Comestai Mobile Health App: Protocol for an Observational Study

Vital Sign and Biochemical Data Collection Using Non-contact Photoplethysmography and the Comestai Mobile Health App: Protocol for an Observational Study

Data collected using the reference devices will be stored without any identifiable participant information and will only be identifiable using the participant identification number provided during screening. The raw data of participants’ vital signs will be locked, encrypted, and accessible only to the study center team. Raw data can be processed only after unlocking the files to calculate the final measured results.

Gianvincenzo Zuccotti, Paolo Osvaldo Agnelli, Lucia Labati, Erika Cordaro, Davide Braghieri, Simone Balconi, Marco Xodo, Fabrizio Losurdo, Cesare Celeste Federico Berra, Roberto Franco Enrico Pedretti, Paolo Fiorina, Sergio Maria De Pasquale, Valeria Calcaterra

JMIR Res Protoc 2025;14:e65229

Telemedicine Booths for Screening Cardiovascular Risk Factors: Prospective Multicenter Study

Telemedicine Booths for Screening Cardiovascular Risk Factors: Prospective Multicenter Study

Various screening programs have been set up over the years to target people who rarely consult a GP. These programs have often focused on detecting hypertension, also known as the “silent killer,” and they have been run in a variety of different settings [15-17]. Some screening programs have involved health checks carried out by nurses, pharmacists, or medical students in settings such as pharmacies, dental surgeries, and community centers [18].

Mélanie Decambron, Christine Tchikladze Merand

JMIR Hum Factors 2025;12:e57032

Daily Automated Prediction of Delirium Risk in Hospitalized Patients: Model Development and Validation

Daily Automated Prediction of Delirium Risk in Hospitalized Patients: Model Development and Validation

As a result, a basic assessment for delirium is recommended for all hospitalized patients aged 65 years or older [5], and formal screening for delirium is recommended for critically ill patients [6]. Despite these recommendations, delirium frequently remains undiagnosed [7]. An automated delirium prediction tool could help address this, by alerting clinicians to at-risk patients so that they could be more carefully assessed for delirium.

Kendrick Matthew Shaw, Yu-Ping Shao, Manohar Ghanta, Valdery Moura Junior, Eyal Y Kimchi, Timothy T Houle, Oluwaseun Akeju, Michael Brandon Westover

JMIR Med Inform 2025;13:e60442

Barriers and Determinants of Referral Adherence in AI-Enabled Diabetic Retinopathy Screening for Older Adults in Northern India During the COVID-19 Pandemic: Mixed Methods Pilot Study

Barriers and Determinants of Referral Adherence in AI-Enabled Diabetic Retinopathy Screening for Older Adults in Northern India During the COVID-19 Pandemic: Mixed Methods Pilot Study

Significant scientific evidence shows that early screening and timely treatment referral can prevent most visual loss caused by DR [11]. Conventionally, DR screening (DRS) includes fundus (retina) examination by ophthalmologists or color fundus photography using conventional cameras (mydriatic or nonmydriatic) conducted by trained eye technicians or optometrists [12].

Anshul Chauhan, Anju Goyal, Ritika Masih, Gagandeep Kaur, Lakshay Kumar, ­ Neha, Harsh Rastogi, Sonam Kumar, Bidhi Lord Singh, Preeti Syal, Vishali Gupta, Luke Vale, Mona Duggal

JMIR Form Res 2025;9:e67047

The AI Reviewer: Evaluating AI’s Role in Citation Screening for Streamlined Systematic Reviews

The AI Reviewer: Evaluating AI’s Role in Citation Screening for Streamlined Systematic Reviews

However, the conventional systematic review methodology is time-consuming, particularly the manual screening of articles for pertinence [2]. The exponential increase in biomedical literature presents a challenge for researchers to remain updated. Artificial intelligence (AI) has shown promise in various fields [3], with large language models (LLMs) specifically offering capabilities to interpret complex text, which can be leveraged in the systematic review process [4].

Jamie Ghossein, Brett N Hryciw, Tim Ramsay, Kwadwo Kyeremanteng

JMIR Form Res 2025;9:e58366

Identifying Data-Driven Clinical Subgroups for Cervical Cancer Prevention With Machine Learning: Population-Based, External, and Diagnostic Validation Study

Identifying Data-Driven Clinical Subgroups for Cervical Cancer Prevention With Machine Learning: Population-Based, External, and Diagnostic Validation Study

Deidentified data were extracted from electronic health records (EHRs) of the national cervical cancer screening program in China. In summary, our study included eligible women aged 25‐65 years who participated in the cervical cancer screening. Data from Fujian Province (2014‐2023) were used to establish a discovery cohort to train the models.

Zhen Lu, Binhua Dong, Hongning Cai, Tian Tian, Junfeng Wang, Leiwen Fu, Bingyi Wang, Weijie Zhang, Shaomei Lin, Xunyuan Tuo, Juntao Wang, Tianjie Yang, Xinxin Huang, Zheng Zheng, Huifeng Xue, Shuxia Xu, Siyang Liu, Pengming Sun, Huachun Zou

JMIR Public Health Surveill 2025;11:e67840

GPT-3.5 Turbo and GPT-4 Turbo in Title and Abstract Screening for Systematic Reviews

GPT-3.5 Turbo and GPT-4 Turbo in Title and Abstract Screening for Systematic Reviews

Manual citation screening, however, is a time-consuming and labor-intensive process, often resulting in human errors and increased workloads [1,2]. Large language models (LLMs) have demonstrated the ability to comprehend and process natural language, underscoring their utility in medical applications [3]. Consequently, LLMs have emerged as promising tools for citation screening in systematic reviews [4].

Takehiko Oami, Yohei Okada, Taka-aki Nakada

JMIR Med Inform 2025;13:e64682