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Impact of Platform Design and Usability on Adherence and Retention: Randomized Web- and Mobile-Based Longitudinal Study

Impact of Platform Design and Usability on Adherence and Retention: Randomized Web- and Mobile-Based Longitudinal Study

Clinical trial retention and adherence rates vary greatly across and within therapeutic areas [1-3]. Low adherence and retention increase costs and negatively impact data quality and the validity of research findings. Mitigating the various retention and adherence challenges in clinical trials is a major focus of clinical trial sponsors and researchers [4]. Studies can improve retention by strategically recruiting individuals or populations more likely to complete a trial [1].

Xinrui Jiang, Michelle Timmons, Elias Boroda, Marie Onakomaiya

J Particip Med 2025;17:e50225

Long-Term Engagement of Diverse Study Cohorts in Decentralized Research: Longitudinal Analysis of “All of Us” Research Program Data

Long-Term Engagement of Diverse Study Cohorts in Decentralized Research: Longitudinal Analysis of “All of Us” Research Program Data

Understanding these changes is essential for examining shifts in participant demographics and engagement over time, which helps identify trends and biases, ensuring the cohort representativeness and development of targeted strategies for improved engagement and retention. Protocol and changes in engagement across components in study. (A) Timeline for components of protocol and journey of a participant in the Ao U program.

Vijay Yadav, Elias Chaibub Neto, Megan Doerr, Abhishek Pratap, Larsson Omberg

Interact J Med Res 2025;14:e56803

Peer Review of “The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: Qualitative Study”

Peer Review of “The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: Qualitative Study”

This is the peer-review report for “The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: Qualitative Study.” This paper [1] has given the impression that the researcher has done thorough homework before starting the research and it is evident in the paper. Case methodology and thematic analysis are a few of the approaches that depict the quality of the paper. Overall, as a reviewer, it is my opinion that the research paper is of quality. 1.

Sanjeev Kumar Thalari

JMIRx Med 2025;6:e70808

Authors’ Response to Peer Reviews of “The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: Qualitative Study”

Authors’ Response to Peer Reviews of “The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: Qualitative Study”

This is the authors’ response to peer-review reports for “The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: Qualitative Study.” This paper [2] has given the impression that the researcher has done thorough homework before starting the research and it is evident in the paper. Case methodology and thematic analysis are a few of the approaches that depict the quality of the paper.

Ajit Kerketta, Raghavendra A N

JMIRx Med 2025;6:e70059

The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: A Qualitative Study

The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: A Qualitative Study

Despite the potential impact of rural alimentation on CHWs’ motivation and retention, there is limited research on this topic in Jharkhand. Therefore, the study seeks to explore the question: “How does access to diverse and organic food in rural Jharkhand influence the motivation and retention of Indigenous community health workers?” The study also aims to explore how Indigenous CHWs in Jharkhand perceive the impact of rural alimentation on their motivation and retention.

Ajit Kerketta, Raghavendra A N

JMIRx Med 2025;6:e48346

Long-Term Knowledge Retention of Biochemistry Among Medical Students in Riyadh, Saudi Arabia: Cross-Sectional Survey

Long-Term Knowledge Retention of Biochemistry Among Medical Students in Riyadh, Saudi Arabia: Cross-Sectional Survey

Many studies agree that biochemistry, among other basic sciences, has a low long-term retention [21-23]. Moreover, building on the previously mentioned impact of the duration of nonuse on retention [24], many studies indicate a strong association between poor biochemistry retention and the low perception of clinical prevalence of biochemistry [23]. Moreover, this low perception of clinical prevalence of biochemistry is also associated with low clinical performance [25-28].

Nimer Mehyar, Mohammed Awawdeh, Aamir Omair, Adi Aldawsari, Abdullah Alshudukhi, Ahmed Alzeer, Khaled Almutairi, Sultan Alsultan

JMIR Med Educ 2024;10:e56132

Challenges and Approaches to Recruitment for and Retention in a Dyad-Focused eHealth Intervention During COVID-19: Randomized Controlled Trial

Challenges and Approaches to Recruitment for and Retention in a Dyad-Focused eHealth Intervention During COVID-19: Randomized Controlled Trial

These characteristics complicated the already challenging recruitment and retention of patients with prostate cancer and their partners. This study examines the challenges, strategies, and outcomes of the RCT recruitment and retention of patients with prostate cancer and their intimate partners during the pandemic.

Chunxuan Ma, Rachel H Adler, Daria B Neidre, Ronald C Chen, Laurel L Northouse, Christine Rini, Xianming Tan, Lixin Song

J Med Internet Res 2024;26:e51877

User Experience of a Large-Scale Smartphone-Based Observational Study in Multiple Sclerosis: Global, Open-Access, Digital-Only Study

User Experience of a Large-Scale Smartphone-Based Observational Study in Multiple Sclerosis: Global, Open-Access, Digital-Only Study

The user retention rate, by comparison, is the fraction of participants who returned to perform the Floodlight Open tests n days after the activation of the Floodlight Open app. The retention rate is extensively used to measure the success of smartphone apps, with higher retention corresponding to higher adoption and level of engagement [28,29].

Adriano Galati, Lito Kriara, Michael Lindemann, Rea Lehner, JB Jones

JMIR Hum Factors 2024;11:e57033

Attrition Rates in HIV Viral Load Monitoring and Factors Associated With Overdue Testing Among Children Within South Africa’s Antiretroviral Treatment Program: Retrospective Descriptive Analysis

Attrition Rates in HIV Viral Load Monitoring and Factors Associated With Overdue Testing Among Children Within South Africa’s Antiretroviral Treatment Program: Retrospective Descriptive Analysis

However, the potential for routine laboratory data for evaluating pediatric attrition in near real time, thereby supporting retention in care, has not previously been described. In the following analysis, we aimed to evaluate HIV viral load (VL) monitoring within the pediatric HIV program by reporting on patient mobility and overdue VL (OVL) testing within 5 high-burden health districts in South Africa.

Ahmad Haeri Mazanderani, Lebohang Radebe, Gayle G Sherman

JMIR Public Health Surveill 2024;10:e40796