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Safety and User Experience of a Generative Artificial Intelligence Digital Mental Health Intervention: Exploratory Randomized Controlled Trial

Safety and User Experience of a Generative Artificial Intelligence Digital Mental Health Intervention: Exploratory Randomized Controlled Trial

At the core of a successful outcome in therapy is the relationship between a client and a therapist [5]. This relationship facilitates client disclosure about their problem, which then enables the therapist to guide the process of self-discovery and remediation from a place of empathy and understanding. The importance of the relationship applies to DMHI as well.

Timothy R Campellone, Megan Flom, Robert M Montgomery, Lauren Bullard, Maddison C Pirner, Aaron Pavez, Michelle Morales, Devin Harper, Catherine Oddy, Tom O'Connor, Jade Daniels, Stephanie Eaneff, Valerie L Forman-Hoffman, Casey Sackett, Alison Darcy

J Med Internet Res 2025;27:e67365

Associations Among Diet, Health, Lifestyle, and Gut Microbiota Composition in the General French Population: Protocol for the Le French Gut – Le Microbiote Français Study

Associations Among Diet, Health, Lifestyle, and Gut Microbiota Composition in the General French Population: Protocol for the Le French Gut – Le Microbiote Français Study

It can be considered as an organ in its own that has coevolved with its host in a symbiotic relationship, contributing to the physiological homeostasis known as “symbiosis” [1]. The gut microbiota is a highly complex ecosystem that can be studied at different levels of resolution. This includes examining diversity parameters, characterizing enterotypes [2,3], exploring various taxonomic ranks ranging from the superkingdom to the species level, and even delving into bacterial strain–specific differences.

Chloe Connan, Sébastien Fromentin, Mourad Benallaoua, Anne-Sophie Alvarez, Nicolas Pons, Benoît Quinquis, Christian Morabito, Julie-Anne Nazare, Elise Borezée-Durant, Le French Gut Consortium, Florence Haimet, Stanislav Dusko Ehrlich, Karine Valeille, Alexandre Cavezza, Hervé Blottière, Patrick Veiga, Mathieu Almeida, Joël Doré, Robert Benamouzig

JMIR Res Protoc 2025;14:e64894

The Dynamics of Doctor-Patient Communication During Remote Consultations: Qualitative Study Among Norwegian Contract General Practitioners

The Dynamics of Doctor-Patient Communication During Remote Consultations: Qualitative Study Among Norwegian Contract General Practitioners

Some practitioners have noted a decline in the doctor-patient relationship linked to text-based consultations [44-46]. However, studies have also shown instances of strengthened therapeutic relationships [24,45] and improved accessibility over time, especially for individuals dealing with long-term health conditions, attributable to enhanced availability [30,31,42-46].

Børge Lønnebakke Norberg, Bjarne Austad, Eli Kristiansen, Paolo Zanaboni, Linn Okkenhaug Getz

J Med Internet Res 2025;27:e57679

Regulating AI in Mental Health: Ethics of Care Perspective

Regulating AI in Mental Health: Ethics of Care Perspective

How does AI affect the therapeutic relationship? How do AI-based “therapist” bots affect patients’ emotions and relationships with others? And how should we treat AI’s “empathy” and “relationships”? Surprisingly, these aspects are almost entirely absent from recent regulatory and ethical guidance and debate.

Tamar Tavory

JMIR Ment Health 2024;11:e58493

Online Ambassador Visits for Hospitalized Children With Cancer: Qualitative Evaluation of Implementation

Online Ambassador Visits for Hospitalized Children With Cancer: Qualitative Evaluation of Implementation

Rather, the hospitalized children explained that they had a close relationship with this study’s nurses, which increased their willingness to participate in online visits. Collaboration between the hospitalized children and this study’s nurses was seen as a facilitator for ensuring participation in the online visits and also fit into the CFIR construct of “teaming” within the implementation process.

Natasha Nybro Boensvang, Mette Weibel, Claire E Wakefield, Pernille Envold Bidstrup, Marianne Olsen, Karin Bækgaard Nissen, Vibeke Spager, Martin Kaj Fridh, Hanne Bækgaard Larsen

JMIR Pediatr Parent 2024;7:e53309

Theoretical Perspectives Underpinning Research on the Physician-Patient Relationship in a Digital Health Practice: Scoping Review

Theoretical Perspectives Underpinning Research on the Physician-Patient Relationship in a Digital Health Practice: Scoping Review

Nevertheless, a physician’s practice must also be guided and adapted based on their relationship with the patient. A sustained physician-patient relationship facilitates the tailoring of therapeutic interventions to best suit individual patients’ needs [4]. Interpersonal skills honed over time through relational interactions with patients cannot be directly replaced by technology.

Damoun Nassehi, Birgitta Haga Gripsrud, Ellen Ramvi

Interact J Med Res 2024;13:e47280

Therapeutic Relational Connection in Telehealth: Concept Analysis

Therapeutic Relational Connection in Telehealth: Concept Analysis

Specifically, it is the quality of the relationship between provider and patient that has been shown to positively affect clinical care outcomes including self-efficacy, adherence, morbidity, functional status, and satisfaction with care [1,2]. Relationship quality may be determined by the degree of connectedness in the context of patient-provider relationships.

Lisa V Duffy, Rebecka Evans, Veronica Bennett, Joan Marie Hady, Priya Palaniappan

J Med Internet Res 2023;25:e43303

The Factors Influencing Older Adults’ Decisions Surrounding Adoption of Technology: Quantitative Experimental Study

The Factors Influencing Older Adults’ Decisions Surrounding Adoption of Technology: Quantitative Experimental Study

The UTAUT allows for age to interact with every relationship in the model. The UTAUT model also posited 4 additional factors important in the behavioral intention to adopt technology: facilitating conditions, social influence, effort expectancy, and performance expectancy.

Jerad Moxley, Joseph Sharit, Sara J Czaja

JMIR Aging 2022;5(4):e39890