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CAH-C: Those aged ≤14 years; with laboratory evidence of recent COVID-19; presenting with a sudden onset of hepatitis, elevated transaminases, and nonobstructive jaundice; lacking marked inflammatory responses; and without evidence of (1) other known causes of acute hepatitis or previous underlying liver disease and (2) multisystem involvement
MIS-C–associated hepatitis: Cases of MIS-C within definitions according to the Centers for Disease Control and Prevention, presenting along with acute hepatitis, that
JMIRx Med 2024;5:e48629
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This study focuses on jaundice, which is characterized by yellow discoloration of the skin and sclera [10]. Understanding jaundice is crucial for medical students, as it may indicate underlying liver disease or biliary obstruction requiring urgent investigation [10]. However, comprehending jaundice can be challenging due to its various causes and complex diagnostics [10].
JMIR Med Educ 2023;9:e44789
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Neonatal jaundice or hyperbilirubinemia is very common in neonatology. Neonatal livers are generally immature, and this condition leads to poor metabolism of bilirubin. Bilirubin is not sufficiently degraded and accumulates excessively in the blood. This clinically manifests as yellowing of the skin and mucous membranes. Based on etiology, jaundice can be divided into physiological and pathological jaundice [1,2].
JMIR Res Protoc 2021;10(5):e24808
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Predictive Models for Neonatal Follow-Up Serum Bilirubin: Model Development and Validation
Management of jaundice is one of the most common, yet vexing, problems in newborn medicine and requires consideration of the myriad contributors to the production and clearance of bilirubin [1]. If not recognized and managed appropriately, hyperbilirubinemia can result in permanent harm. A large proportion of neonatal readmissions is related to jaundice [2]. Bilirubin arises from the catabolism of iron protoporphyrin (heme) from hemoglobin in red blood cells.
JMIR Med Inform 2020;8(10):e21222
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