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Gender Differences in X (Formerly Twitter) Use, Influence, and Engagement Among Cardiologists From the Top U.S. News Best Hospitals

Gender Differences in X (Formerly Twitter) Use, Influence, and Engagement Among Cardiologists From the Top U.S. News Best Hospitals

News Best Hospitals for cardiology, heart surgery, and vascular surgery were identified from the 2023 ranking (Table 1) [7]. Available physician website profiles of fellowship-trained adult medicine cardiologists were manually reviewed by 3 investigators (MS, HT, and OP) for inclusion, and demographic information was collected (eg, academic appointment, apparent gender, and medical school and fellowship graduation years).

Minji Seok, Sungjin Kim, Harper Tzou, Olivia Peony, Mitchell Kamrava, Andriana P Nikolova, Katelyn M Atkins

JMIR Cardio 2025;9:e66308

The Influence of eHealth Stress Management Interventions on Psychological Health Parameters in Patients With Cardiovascular Disease: Systematic Review and Meta-Analysis

The Influence of eHealth Stress Management Interventions on Psychological Health Parameters in Patients With Cardiovascular Disease: Systematic Review and Meta-Analysis

The keywords we have chosen for the free text search are as follows: “e Health,” “e-Health,” “m Health,” “telehealth,” “digital health intervention,” “mobile,” “app,” “web,” “web-based,” “online,” “phone,” “internet,” “internet-based cognitive behavioral therapy,” “web-based cognitive behavioral therapy,” “online cognitive behavioral therapy,” “digital cognitive behavioral therapy,” “cardiovascular disease,” “heart disease,” “coronary heart disease,” “coronary artery disease,” “ischemic heart disease,” “heart

Ouahiba El-Malahi, Darya Mohajeri, Alexander Bäuerle, Raluca Ileana Mincu, Christos Rammos, Christoph Jansen, Martin Teufel, Tienush Rassaf, Julia Lortz

J Med Internet Res 2025;27:e67118

AI-Assisted Hypothesis Generation to Address Challenges in Cardiotoxicity Research: Simulation Study Using ChatGPT With GPT-4o

AI-Assisted Hypothesis Generation to Address Challenges in Cardiotoxicity Research: Simulation Study Using ChatGPT With GPT-4o

Cardiotoxicity is critically important in heart disease research. Cardiotoxicity can lead to severe and sometimes irreversible damage to the heart muscle, resulting in conditions such as heart failure, arrhythmias, and even death [1,2]. For patients with preexisting heart conditions, it is essential to understand how new treatments might impact their cardiovascular health.

Yilan Li, Tianshu Gu, Chengyuan Yang, Minghui Li, Congyi Wang, Lan Yao, Weikuan Gu, DianJun Sun

J Med Internet Res 2025;27:e66161

Augmenting Engagement in Decentralized Clinical Trials for Atrial Fibrillation: Development and Implementation of a Programmatic Architecture

Augmenting Engagement in Decentralized Clinical Trials for Atrial Fibrillation: Development and Implementation of a Programmatic Architecture

The intervention incorporates a relational agent [21]—an animated health educator that uses synthetic speech and conversational gestures, such as hand movements, gaze shifts, natural pauses, and emphatic facial expressions to simulate face-to-face counseling—in conjunction with a mobile heart rhythm sensor. We describe here the programmatic architecture to conduct remote trials and the resulting augmentation of geographic, ethnic, and racial diversity of participants.

Toluwa Daniel Omole, Andrew Mrkva, Danielle Ferry, Erin Shepherd, Jessica Caratelli, Noah Davis, Richmond Akatue, Timothy Bickmore, Michael K Paasche-Orlow, Jared W Magnani

JMIR Cardio 2025;9:e66436

Psychological eHealth Interventions for Patients With Cardiovascular Diseases: Systematic Review and Meta-Analysis

Psychological eHealth Interventions for Patients With Cardiovascular Diseases: Systematic Review and Meta-Analysis

This chronic activation results in elevated heart rate and blood pressure, reducing heart rate variability and increasing the risk of cardiovascular complications such as hypertension. Additionally, psychological distress activates the hypothalamic-pituitary-adrenal (HPA) axis, increasing cortisol production.

Jing Jing Su, Rose Lin, Ladislav Batalik, Arkers Kwan Ching Wong, Sherry L Grace

J Med Internet Res 2025;27:e57368

Effect of a Telemedicine Model on Patients With Heart Failure With Reduced Ejection Fraction in a Resource-Limited Setting in Vietnam: Cohort Study

Effect of a Telemedicine Model on Patients With Heart Failure With Reduced Ejection Fraction in a Resource-Limited Setting in Vietnam: Cohort Study

The universal definition of heart failure (HF) describes it as a clinical syndrome characterized by symptoms or signs caused by structural or functional cardiac abnormalities, corroborated by elevated natriuretic peptide levels or objective evidence of pulmonary or systemic congestion [1,2]. HF has long been regarded as a global pandemic, with an estimated 64 million individuals worldwide with this condition, and this number continues to rise [3].

Hoai Thi Thu Nguyen, Hieu Ba Tran, Phuong Minh Tran, Hung Manh Pham, Co Xuan Dao, Thanh Ngoc Le, Loi Doan Do, Ha Quoc Nguyen, Thom Thi Vu, James Kirkpatrick, Christopher Reid, Dung Viet Nguyen

J Med Internet Res 2025;27:e67228

Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

With landmark clinical trials [3-6] demonstrating the efficacy of the latter drugs, there has been a paradigm shift in initiating and sequencing optimal anti–heart failure therapy and a concomitant reevaluation of the evidence base that guides conventional heart failure management. The American Heart Association heart failure guideline supports the rapid titration of guideline-based therapies every 1-2 weeks, with the goal of achieving target doses [7].

Sumanth Karamchand, Tsungai Chipamaunga, Poobalan Naidoo, Kiolan Naidoo, Virendra Rambiritch, Kevin Ho, Robert Chilton, Kyle McMahon, Rory Leisegang, Hellmuth Weich, Karim Hassan

JMIR Res Protoc 2025;14:e44027

Exploring Stakeholder Perspectives on the Barriers and Facilitators of Implementing Digital Technologies for Heart Disease Diagnosis: Qualitative Study

Exploring Stakeholder Perspectives on the Barriers and Facilitators of Implementing Digital Technologies for Heart Disease Diagnosis: Qualitative Study

However, the most common first stage of medical care is the diagnosis of symptoms that may reflect underlying heart disease, with an estimated 39% of adults experiencing symptoms that can reflect possible underlying heart disease such as chest pain [20]. Therefore, the initial onset of symptoms that may indicate cardiovascular problems affects a far greater number of people than those dealing with recovery from or management of heart disease.

Kamilla Abdullayev, Tim J A Chico, Jiana Canson, Matthew Mantelow, Oli Buckley, Joan Condell, Richard J Van Arkel, Vanessa Diaz-Zuccarini, Faith Matcham

JMIR Cardio 2025;9:e66464