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Skip search results from other journals and go to results- 11 Journal of Medical Internet Research
- 7 JMIR Formative Research
- 6 JMIR Mental Health
- 4 JMIR Medical Education
- 3 JMIR Serious Games
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For the patient-education bot, the following five criteria (maximum score: 15) were used: (1) medical information accuracy, (2) clarity and simplicity of explanations, (3) expressions of empathy and warmth, (4) explanation of purpose or importance of procedures, and (5) adherence to professional role boundaries.
JMIR Nursing 2025;8:e63058
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Empathy is a key factor in quality of care and patient-centered care [1]. Greater empathy is associated with better clinical outcomes and patient-care experiences [2]. Empathy is an innate characteristic of the individual, and it is dynamic, constantly evolving, and built under the influence of various personal and environmental factors [3]. Empathy can be considered to include 3 dimensions: affective, cognitive, and behavioral [4,5].
JMIR Serious Games 2025;13:e62688
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Of note, better attitudes and empathy of health care staff toward patients with psychotic disorders have been associated with better patient well-being, quality of patient care, and treatment outcomes [4-6].
In turn, attitude and empathy levels can also be influenced by the level of stigma [7]. Stigma has been commonly associated with psychotic disorders [8].
JMIR Ment Health 2025;12:e66925
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Large Language Models and Empathy: Systematic Review
Lee et al [38] used Chain-of-Empathy prompting to reason emotion and situational factors that may assist the model to infer the emotional experience. They evaluated GPT-3.5 and compared 4 unique prompts that used Chain-of-Empathy in generating empathetic responses to Reddit posts. The Chain-of-Empathy strategy resulted in improved the model’s empathy expression [38].
J Med Internet Res 2024;26:e52597
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Reference 1: A culture of compassion: how timeless principles of kindness and empathy become powerful Reference 8: A systematic review of educational interventions and their impact on empathy and compassionempathy
JMIR Form Res 2024;8:e60670
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“Doctor ChatGPT, Can You Help Me?” The Patient’s Perspective: Cross-Sectional Study
(G + H): Data collection: patients rated responses for empathy and usefulness, while physicians provided feedback encompassing empathy, usefulness, correctness, and potential harm. ENT: otolaryngology; EP: expert panel; GS: general surgery; Internal: internal medicine; Ped: pediatrics; trauma: traumatology.
Two-sided t tests were used to compare 2 variables (eg, mean usefulness and empathy scores of responses of the EP with the ones of Chat GPT).
J Med Internet Res 2024;26:e58831
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The study’s 4 comparisons are as follows:
H-CR: we compared empathy toward the narrator across human-written retrieved stories and Chat GPT-retrieved stories
H-CR+T: we compared empathy toward the narrator across human-written retrieved stories and Chat GPT-retrieved stories, making transparent to the user whether the story they read was written by a human or AI before they rated their empathy (repeat H-CR with transparency)
H-CG: we compared empathy toward the narrator across human-written retrieved stories and
JMIR Ment Health 2024;11:e62679
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Only 5 (26%) of the 19 studies referred to an explicit definition of empathy, as summarized in Textbox 1.
Studies and definition of empathy
Jiang et al [21], 2022
Empathy processing is a situation-specific, cognitive-affective state or process with the projection of oneself into another’s feelings, actions, and experiences.
JMIR Ment Health 2024;11:e58974
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Responses were scored on four 10-point Likert scales for (1) appropriateness and completeness, (2) empathy, (3) satisfaction, and (4) an overall ranking item. The 10-point Likert scale ranged from 1=very poor, not empathetic, very dissatisfied to 10=very good, very empathetic, very satisfied. A 10-point Likert scale without a midpoint was chosen to avoid a neutral stand and allow an unequivocal selection [16].
J Med Internet Res 2024;26:e56413
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