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Patient-Related Barriers to Digital Technology Adoption in Alzheimer Disease: Systematic Review
Given our theoretical framework and the growing body of literature on digital technologies in dementia, the search was focused on AD studies, aiming to improve consistency among findings.
Keywords for the literature search.
JMIR Aging 2025;8:e64324
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Twenty-four-hour sleep/wake characteristics, which are objectively measurable using accelerometer-containing devices, are related to both dementia biomarkers and dementia risk. Prior studies have shown that sleep/wake rhythm disruption, including fragmentation of 24-hour sleep/wake rhythms, temporally precedes the incidence of mild cognitive impairment (MCI) and dementia [1,2]. Even among adults with normal cognition, rhythm fragmentation correlates with greater brain amyloid deposition [3,4].
JMIR Aging 2025;8:e67294
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The World Health Organization (WHO) estimates 55 million people are living with dementia worldwide, with an increase to 78 million by 2030 [1]. In Germany, approximately two-thirds of the 1.8 million people with dementia are cared for at home by an informal caregiver, most often a relative [2]. Numerous studies have shown that caring for a relative with dementia is associated with a multitude of time- and resource-intensive challenges [3-5].
JMIR Aging 2025;8:e59942
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Studies have long noted deficiencies and delays in individuals receiving a dementia diagnosis [3-12]. The World Health Organization’s Global Action Plan on Dementia includes a focus on the right to a timely dementia diagnosis to enable better planning, treatment, care, support, and quality of life [13]; for example, timely diagnosis can help individuals avoid preventable accidents and injuries leading to care escalation and can reduce distress for patients and caregivers [9,14-16].
JMIR Res Protoc 2025;14:e60471
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These materials aimed to enhance their understanding of dementia (eg, types, stages, and symptoms), care strategies for different stages of dementia, strategies for managing behavioral and psychological symptoms of dementia, and communication techniques. Participants in the control group continued with care as usual and received the same psychoeducation materials provided by the study team.
JMIR Form Res 2025;9:e67545
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Addressing the Digital Divide Among the Older Population Presents a Substantial Challenge
dementia
J Med Internet Res 2025;27:e69482
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Approximately one-third of these caregivers of individuals living with dementia acknowledge postponing or neglecting their health due to their caregiving role [1]. Given African American individuals’ heightened risk of ADRD, particularly vascular and mixed dementia, this problem disproportionately affects African American family caregivers [1].
JMIR Res Protoc 2025;14:e66975
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Dementia affects multiple aspects of individual and family well-being, serving as an indicator of multimorbidity in both people with dementia and their carers. People with dementia have twice the number of chronic physical and mental conditions compared to those without dementia [9,10].
JMIR Res Protoc 2025;14:e60296
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As the population ages, diseases such as dementia are diagnosed more often because age is their strongest known risk factor [2,3]. Dementia is a major cause of disability and dependency, affecting cognitive abilities and behavior, leading to an inability to signal when help is needed, which is associated with safety concerns [3,4]. Compared with 2015, the number of people affected with dementia will triple by 2050 [3].
JMIR Aging 2025;8:e64074
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