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Skip search results from other journals and go to results- 13 JMIR Research Protocols
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simultaneous application of transcutaneous electrical nerve stimulation (TENS) on specific lumbar and acupuncture Reference 23: Acupressure and acupuncture use in the peripartum periodacupuncture acupuncture points
JMIR Res Protoc 2025;14:e63050
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Acupuncture offers advantages such as multitarget, multipathway, and holistic regulation in the management of hypertension [27]. Nonetheless, the current scientific basis for the modulation of primary hypertension by acupuncture is insufficient [28,29]. There are limited intervention trials comparing acupuncture with sham acupuncture in the regulation of hypertension [24].
JMIR Res Protoc 2025;14:e71850
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Although the clinical practice guideline developed by Tunkel et al [19] does not mention acupuncture for the treatment of persistent tinnitus due to the lack of high-quality randomized controlled trials (RCTs), the expert panel acknowledged that many patients with persistent or bothersome tinnitus seek acupuncture therapy.
JMIR Res Protoc 2025;14:e69163
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Acupuncture therapy has been used to treat glaucoma for thousands of years and has demonstrated favorable safety and convenience [5]. Acupuncture can modify glaucoma blood flow parameters to protect the optic nerve, such as increasing the flow of blood in the eye [6] and reducing anomalies of blood flow in the central artery of the retina [7]. Acupuncture treatments relay electrical signals via the dorsal root ganglion (DRG) and spinal cord, finally regulating ocular blood flow [8].
JMIR Res Protoc 2025;14:e67737
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Furthermore, acupuncture can also regulate inflammatory cytokines such as interleukin-1, interleukin-6, and tumor necrosis factor-α [58-62], and it can influence the gut microbiota to regulate sleep-wake behavior [63,64].
Much of the research supporting the use of acupuncture for insomnia is constrained by the limitations of low- or moderate-quality evidence and inconsistent reports regarding its clinical efficacy and safety. Furthermore, the effects of acupuncture on PCI remain largely unknown.
JMIR Res Protoc 2025;14:e69417
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The aim of this study is to investigate the acute neural mechanisms of acupuncture stimulation concerning CR and to identify the neural substrates of CR in the group without cognitive impairment and the group with cognitive impairment using f NIRS.
The participants will be divided into 2 equal groups: the verum acupuncture group (study group) and the sham acupuncture group (control group).
JMIR Res Protoc 2025;14:e66838
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Acupuncture as Adjuvant Therapy for Glaucoma: Protocol for a Randomized Controlled Trial
Possible mechanisms for acupuncture treatment have been proposed, including the release of neurochemical substances through acupuncture stimulation; the influence of acupuncture on ocular blood flow parameters [9,10]; and the upregulation of neurotrophic factors, such as nerve growth factor and brain-derived neurotrophic factor expression in the retina [11].
JMIR Res Protoc 2024;13:e57888
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In particular, acupuncture has the unique advantages of simplicity, convenience, safety, and effectiveness in the treatment of VCI [11].
JMIR Res Protoc 2024;13:e56484
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Acupuncture is the most prevalent form of traditional medicine practice, with 183 of 202 (90.5%) surveyed countries recognizing its use, as reported by the World Federation of Acupuncture-Moxibustion Societies [3]. A bibliometric analysis reported that of 2189 positive recommendations for the use of acupuncture, about 68% were associated with 107 pain indications [4].
JMIR Res Protoc 2024;13:e54352
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Acupuncture is widely practiced in the prevention and treatment of PMI [24] and is effective in the treatment of PMI and various sleep disorders through significantly reducing Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI) scores [25-27], improving sleep efficiency and overall nighttime sleep time in insomnia patients and reducing night-time wakefulness. Acupuncture is also a safe and effective treatment for perimenopausal depression with short- to medium-term efficacy [28].
JMIR Res Protoc 2023;12:e51767
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