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Consumer Data is Key to Artificial Intelligence Value: Welcome to the Health Care Future

Consumer Data is Key to Artificial Intelligence Value: Welcome to the Health Care Future

A crucial component of contemporary health data policy is the adoption of Fast Healthcare Interoperability Resource (FHIR), one of the most significant advancements in EMR data exchange [24]. Developed and maintained by Health Level 7 International (HL7), FHIR is an open, license-free standard that is publicly available and designed to promote seamless interoperability.

James C

J Particip Med 2025;17:e68261

Designing Clinical Decision Support Systems (CDSS)—A User-Centered Lens of the Design Characteristics, Challenges, and Implications: Systematic Review

Designing Clinical Decision Support Systems (CDSS)—A User-Centered Lens of the Design Characteristics, Challenges, and Implications: Systematic Review

Therefore, understanding how standards such as fast healthcare interoperability resources (FHIR), digital health technologies such as electronic health records (EHRs) systems, and emerging artificial intelligence (AI) applications such as explainable artificial intelligence (XAI) integrate with CDSS is essential for effective implementation. This review seeks to expand on existing literature by examining CDSS design through the unique lens of a UCD perspective.

Andrew A Bayor, Jane Li, Ian A Yang, Marlien Varnfield

J Med Internet Res 2025;27:e63733

Toward Interoperable Digital Medication Records on Fast Healthcare Interoperability Resources: Development and Technical Validation of a Minimal Core Dataset

Toward Interoperable Digital Medication Records on Fast Healthcare Interoperability Resources: Development and Technical Validation of a Minimal Core Dataset

In 2011, due to the rapidly growing amount of health data, HL7 started developing the Fast Interoperability Resources (FHIR), a standard that addresses the need for faster and better methods for interoperable data exchange. FHIR was designed to be flexible and adaptable, making this standard easy to implement and suitable for a wide range of clinical processes. It uses a modern web-based application programming interface (API) [17].

Eduardo Salgado-Baez, Raphael Heidepriem, Renate Delucchi Danhier, Eugenia Rinaldi, Vishnu Ravi, Akira-Sebastian Poncette, Iris Dahlhaus, Daniel Fürstenau, Felix Balzer, Sylvia Thun, Julian Sass

JMIR Med Inform 2025;13:e64099

Data Interoperability in Context: The Importance of Open-Source Implementations When Choosing Open Standards

Data Interoperability in Context: The Importance of Open-Source Implementations When Choosing Open Standards

Reflecting on this condition in the context of open health data ecosystems, we observe a salient difference between FHIR versus open EHR and OMOP, namely that the former is the only one that has been mandated—or at least strongly recommended—in some jurisdictions. Survey results on the state of FHIR show that the FHIR standard has been mandated or advised in 20 countries [9].

Daniel Kapitan, Femke Heddema, André Dekker, Melle Sieswerda, Bart-Jan Verhoeff, Matt Berg

J Med Internet Res 2025;27:e66616

A Validation Tool (VaPCE) for Postcoordinated SNOMED CT Expressions: Development and Usability Study

A Validation Tool (VaPCE) for Postcoordinated SNOMED CT Expressions: Development and Usability Study

Ontoserver is currently the only Fast Healthcare Interoperability Resource (FHIR) terminology server that supports postcoordination at all. Ontoserver is used to validate the PCEs in combination with the FHIR service $validate-code [11]. This checks a PCE against specific coding systems, such as SNOMED CT. This method provides a validation result through a Representational State Transfer (REST) request that returns a JSON object [11].

Tessa Ohlsen, Viola Hofer, Josef Ingenerf

JMIR Med Inform 2025;13:e67984

A Computable Phenotype Algorithm for Postvaccination Myocarditis/Pericarditis Detection Using Real-World Data: Validation Study

A Computable Phenotype Algorithm for Postvaccination Myocarditis/Pericarditis Detection Using Real-World Data: Validation Study

FDA: US Food and Drug Administration; FHIR: Fast Healthcare Interoperability Resources. The methods section is crucial for ensuring the accuracy and reliability of research findings. This study’s methodology encompasses the following aspects: computable phenotype development, phenotype distributed deployment, study period, data, and the process of reviewing medical records.

Matthew Deady, Raymond Duncan, Matthew Sonesen, Renier Estiandan, Kelly Stimpert, Sylvia Cho, Jeffrey Beers, Brian Goodness, Lance Daniel Jones, Richard Forshee, Steven A Anderson, Hussein Ezzeldin

J Med Internet Res 2024;26:e54597

Establishing Medical Intelligence—Leveraging Fast Healthcare Interoperability Resources to Improve Clinical Management: Retrospective Cohort and Clinical Implementation Study

Establishing Medical Intelligence—Leveraging Fast Healthcare Interoperability Resources to Improve Clinical Management: Retrospective Cohort and Clinical Implementation Study

While FHIR holds the potential to standardize data, various challenges persist. Most frequently named is the implementation of FHIR as an application, the complexity of the FHIR standard (including its nested structure), and the representational state transfer (RESTful) approach [14]. In particular, the complexity of the data structure makes it not readily available for processing and easy access to the end user.

Alexander Brehmer, Christopher Martin Sauer, Jayson Salazar Rodríguez, Kelsey Herrmann, Moon Kim, Julius Keyl, Fin Hendrik Bahnsen, Benedikt Frank, Martin Köhrmann, Tienush Rassaf, Amir-Abbas Mahabadi, Boris Hadaschik, Christopher Darr, Ken Herrmann, Susanne Tan, Jan Buer, Thorsten Brenner, Hans Christian Reinhardt, Felix Nensa, Michael Gertz, Jan Egger, Jens Kleesiek

J Med Internet Res 2024;26:e55148

A Generic Transformation Approach for Complex Laboratory Data Using the Fast Healthcare Interoperability Resources Mapping Language: Method Development and Implementation

A Generic Transformation Approach for Complex Laboratory Data Using the Fast Healthcare Interoperability Resources Mapping Language: Method Development and Implementation

HL7 FHIR is the emerging standard for health care–specific data exchange and has been broadly adapted worldwide [8]. FHIR provides state-of-the-art technologies to modernize the current health care landscape using extensible resources as harmonized and semantically annotatable information units [9]. However, FHIR also provides mechanisms to natively define transformations on its structures.

Jesse Kruse, Joshua Wiedekopf, Ann-Kristin Kock-Schoppenhauer, Andrea Essenwanger, Josef Ingenerf, Hannes Ulrich

JMIR Med Inform 2024;12:e57569