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Toward Ambulatory Baroreflex Sensitivity: Comparison Between Indices of Arterial Line and Photoplethysmography in Male Volunteers

Toward Ambulatory Baroreflex Sensitivity: Comparison Between Indices of Arterial Line and Photoplethysmography in Male Volunteers

In addition, this study, in extension, also aims to assess the feasibility of assessing BRS patterns over 24 hours by means of a single volunteer. This study involves a secondary analysis of an existing dataset [31]. The primary analysis focused on evaluating the accuracy of PPG-derived HR variability (HRV) [31], while in this analysis, the baroreceptor sensitivity is quantified by measuring HR changes following alterations in arterial line pressure or less invasive alternatives.

Jolanda Witteveen, Fabian Beutel, Evelien Hermeling

JMIR Cardio 2025;9:e54771

Evaluating the Usability of an HIV Prevention Artificial Intelligence Chatbot in Malaysia: National Observational Study

Evaluating the Usability of an HIV Prevention Artificial Intelligence Chatbot in Malaysia: National Observational Study

Our team has been conducting research on AI chatbots since 2020, and we have created an AI chatbot and tested its feasibility and acceptability for promoting HIV testing among MSM in Malaysia. We found that such an AI chatbot is acceptable by MSM [3,6]. To further enhance the algorithms and features of the AI chatbot, it is essential to test its usability among a large number of end-users using predefined metrics.

Zhao Ni, Sunyoung Oh, Rumana Saifi, Iskandar Azwa, Frederick L Altice

JMIR Hum Factors 2025;12:e70034

Reducing Methamphetamine Use in Aboriginal and Torres Strait Islander Communities With the “We Can Do This” Web App: Qualitative Evaluation of Acceptability and Feasibility

Reducing Methamphetamine Use in Aboriginal and Torres Strait Islander Communities With the “We Can Do This” Web App: Qualitative Evaluation of Acceptability and Feasibility

This acceptability and feasibility study arose from a strong interest from clinicians working with Aboriginal and Torres Strait Islander people who use methamphetamine and their desire to have access to the web application as an adjunct to client consultations. Process evaluations are an essential part of testing complex interventions [18] as they identify why an intervention might work and how it can be improved [19].

Leda Sivak, Rachel Reilly, Shani Crumpen, Carla Treloar, Rebecca McKetin, Julia Butt, Yvette Roe, Nadine Ezard, Brendan Quinn, Jack Nagle, Wade Longbottom, Clifford Warrior, James Ward

JMIR Form Res 2025;9:e58369

Assessing Postoperative Pain in Patients Who Underwent Total Knee Arthroplasty Using an Automated Self-Logging Patient-Reported Outcome Measure Collection Device: Retrospective Cohort Study

Assessing Postoperative Pain in Patients Who Underwent Total Knee Arthroplasty Using an Automated Self-Logging Patient-Reported Outcome Measure Collection Device: Retrospective Cohort Study

In this study, we compared tourniquet use in TKA to showcase the clinical utility and feasibility of the Pain Pad device in collecting pain levels. Using tourniquets in TKA remains a topic of considerable debate. Some orthopedic surgeons advocate for their use, citing advantages such as improved surgical field visualization, enhanced cementation through increased interdigitation, reduced intraoperative blood loss, and shorter operative times [41].

Prabjit Ajrawat, Blaine Price, Daniel Gooch, Rudolf Serban, Ruqaiya Al-Habsi, Oliver Pearce

JMIR Hum Factors 2025;12:e65271

Influence of Personal Traits, Social Relationships, and External Resources on the Development of Emotional Resilience in Children From East London: Protocol for an Observational Accelerated Longitudinal Cohort Study

Influence of Personal Traits, Social Relationships, and External Resources on the Development of Emotional Resilience in Children From East London: Protocol for an Observational Accelerated Longitudinal Cohort Study

Additionally, our research aims to better understand the psychometric properties of resilience measures used in a preadolescent sample and assess the feasibility of developing a longitudinal cohort study of preadolescent children in East London. The DEER study is an observational cohort study that uses an accelerated longitudinal design.

Francois van Loggerenberg, Milena Nikolajeva, Daniele Porricelli, Imogen Hensler, Aisling Murray, Eleanor Keiller, Julia Michalek, Dennis Ougrin, Jennifer Y F Lau

JMIR Res Protoc 2025;14:e70797

Investigating Challenges in Implementing a Digital Play Intervention in a Complex Organization Across Pediatric Departments: Non-Randomized Controlled Feasibility Trial

Investigating Challenges in Implementing a Digital Play Intervention in a Complex Organization Across Pediatric Departments: Non-Randomized Controlled Feasibility Trial

This small-scale feasibility study is a non-RCT conducted from October to December 2023. As noted, we applied the 8 focus areas by Bowen et al [18] to describe and evaluate the feasibility of a digital play intervention called Monster Gardener. The data from this feasibility study were reported using the CONSORT (Consolidated Standards of Reporting Trials) statement extension to pilot and feasibility trials [19].

Laerke Winther, Michelle Stahlhut, Derek John Curtis, Christian Have Dall, Thomas Leth Frandsen, Jette Led Sorensen

JMIR Rehabil Assist Technol 2025;12:e58019

Assessing the Efficacy of the INTELLECT Cognitive Behavioral Therapy Mobile App for Anxiety and Depressive Symptoms Among At-Risk Japanese Employees: Randomized Controlled Trial

Assessing the Efficacy of the INTELLECT Cognitive Behavioral Therapy Mobile App for Anxiety and Depressive Symptoms Among At-Risk Japanese Employees: Randomized Controlled Trial

Our secondary objectives encompass evaluating whether these features also lead to improvements in CBT skills and assessing the acceptability, feasibility, and satisfaction levels among its users. This study was an RCT with two groups: (1) a group engaging with self-help CBT features on an INTELLECT app for 3 weeks (intervention group) and (2) a no-treatment and assessment-only (AO) group (control group).

Kengo Yokomitsu, Riki Oimatsu, Sean Han Yang Toh, Oliver Sündermann

JMIR Mhealth Uhealth 2025;13:e60871

A Low-Cost, Social Media–Supported Intervention for Caregivers to Enhance Toddlers’ Language Learning: Mixed Methods Feasibility and Acceptability Study

A Low-Cost, Social Media–Supported Intervention for Caregivers to Enhance Toddlers’ Language Learning: Mixed Methods Feasibility and Acceptability Study

In this feasibility and acceptability study, we describe the development and the use of a cost-effective, media-supported approach to sharing information and strategies with caregivers to support language learning in toddlers aged between 12 and 18 months, a critical developmental inflection point.

Mollie Romano, Diana Abarca, Frances Baehman

JMIR Pediatr Parent 2025;8:e66175

Collecting at-Home Biometric Measures for Longitudinal Research From the i3C: Feasibility and Acceptability Study

Collecting at-Home Biometric Measures for Longitudinal Research From the i3C: Feasibility and Acceptability Study

Mobile health (m Health) approaches have been proposed as a means to overcome some of these barriers [4], but the feasibility of collecting a broad range of measurements using at-home devices has not been sufficiently evaluated in this setting. Therefore, we conducted a study to evaluate the feasibility of a “Virtual Home Clinic” by sending biometric measurement devices to participants’ homes.

Marta Russell, Erin Cain, Lydia Bazzano, Ileana De Anda, Jessica G Woo, Elaine M Urbina

JMIR Hum Factors 2025;12:e71103

Using Ecological Momentary Assessment to Assess Family Functioning in Spanish-Speaking Parent and Adolescent Dyads: Daily Questionnaire Study

Using Ecological Momentary Assessment to Assess Family Functioning in Spanish-Speaking Parent and Adolescent Dyads: Daily Questionnaire Study

An additional limitation of existing EMA research is the limited evidence available on EMA protocols being implemented and tested for feasibility and acceptability in Spanish-speaking (monolingual and bilingual) populations (ie, English and Spanish) [18].

Alejandra Fernandez, Savannah Bernal, Lana Kim, Subodh Potla

JMIR Form Res 2025;9:e60073