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Multimodal Web-Based Telerehabilitation for Patients With Post–COVID-19 Condition: Protocol for a Randomized Controlled Trial

Multimodal Web-Based Telerehabilitation for Patients With Post–COVID-19 Condition: Protocol for a Randomized Controlled Trial

Assuming a power of 0.8 and a medium to large effect (Cohen f=0.35) on the VO2peak (in accordance with the work by Bacon et al [74]), 67 participants are needed. Considering the calculated required sample size and a dropout rate of 15% to 20% [53,75], the target number of study participants is set at a total of 80, or 40 participants per group. Adherence to the intervention is defined as the percentage of training sessions completed of the prescribed training sessions [75].

Aleksandar Tomaskovic, Vincent Weber, David T Ochmann, Elmo Wanja Neuberger, Ella Lachtermann, Alexandra Brahmer, Nils Haller, Barlo Hillen, Kira Enders, Viktoria Eggert, Peter Zeier, Klaus Lieb, Perikles Simon

JMIR Res Protoc 2025;14:e65044