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Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Preliminary results suggest that the 5-Cog paradigm is a cost-effective option compared to “enhanced usual care” for the early detection of cognitive impairment in primary care (H Congivaram, BS, unpublished data, December 2024). Investigators have begun collecting cost estimates for 5-Cog procedures and resulting health care costs in the IUH system, as these were not previously collected.

Rachel Beth Rosansky Chalmer, Emmeline Ayers, Erica F Weiss, Nicole R Fowler, Andrew Telzak, Diana Summanwar, Jessica Zwerling, Cuiling Wang, Huiping Xu, Richard J Holden, Kevin Fiori, Dustin D French, Celeste Nsubayi, Asif Ansari, Paul Dexter, Anna Higbie, Pratibha Yadav, James M Walker, Harrshavasan Congivaram, Dristi Adhikari, Mairim Melecio-Vazquez, Malaz Boustani, Joe Verghese

JMIR Res Protoc 2025;14:e60471

Theory-Based Social Media Intervention for Nonmedical Use of Prescription Opioids in Young Adults: Protocol for a Randomized Controlled Trial

Theory-Based Social Media Intervention for Nonmedical Use of Prescription Opioids in Young Adults: Protocol for a Randomized Controlled Trial

Eligible leaders will be those who are (1) aged between 18 and 25 years, (2) formally trained as a recovery coach (>40 h), (3) have had successful recovery from opioid misuse or opioid use disorder, and (4) use social media (eg, Instagram, Facebook, and Snapchat) on a daily basis.

Cheuk Chi Tam, Sean D Young, Sayward Harrison, Xiaoming Li, Alain H Litwin

JMIR Res Protoc 2025;14:e65847