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Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial

Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial

In the long term, SAD can lead to profound social isolation; missed opportunities; and comorbid conditions such as depression, generalized anxiety disorder, and substance abuse [1,3,4]. While symptoms do not typically improve in the absence of treatment [5,6], cognitive behavioral therapy for social anxiety (CBT-SA) has been established as an effective treatment with moderate to large effects on social anxiety symptoms [7-9].

Mona M Garvert, Jessica McFadyen, Stuart Linke, Tayla McCloud, Sofie S Meyer, Sandra Sobanska, Paul B Sharp, Alex Long, Quentin J M Huys, Mandana Ahmadi

J Med Internet Res 2025;27:e64138

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Model-Based Feature Extraction and Classification for Parkinson Disease Screening Using Gait Analysis: Development and Validation Study

Model-Based Feature Extraction and Classification for Parkinson Disease Screening Using Gait Analysis: Development and Validation Study

Using Mel-frequency cepstral coefficients and delta Mel-frequency cepstral coefficients, the authors proposed a deep learning model combining a recurrent neural network (RNN) with a long short-term memory (LSTM) layer. Comparative evaluation of alternative ML techniques, including SVM, KNN and RNN with stochastic gradient descent, revealed superior performance of the proposed RNN-LSTM model, optimized with the adaptive moment estimation optimizer.

Ming De Lim, Tee Connie, Michael Kah Ong Goh, Nor ‘Izzati Saedon

JMIR Aging 2025;8:e65629

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Effectiveness of Virtual Reality–Complemented Pulmonary Rehabilitation on Lung Function, Exercise Capacity, Dyspnea, and Health Status in Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis

Effectiveness of Virtual Reality–Complemented Pulmonary Rehabilitation on Lung Function, Exercise Capacity, Dyspnea, and Health Status in Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis

Specifically, studies with larger sample sizes and longer follow-up periods are needed to evaluate the long-term effectiveness and sustainability of VR-complemented PR. Developing standardized VR protocols that define exercise intensity, frequency, duration, and content would help reduce heterogeneity and improve the comparability of results across studies.

Yuyin Chen, Yuanyuan Zhang, Xiuhong Long, Huiqiong Tu, Jibing Chen

J Med Internet Res 2025;27:e64742

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Factors Influencing Primary Care Physicians’ Intent to Refer Patients With Hypertension to a Digital Remote Blood Pressure Monitoring Program: Mixed Methods Study

Factors Influencing Primary Care Physicians’ Intent to Refer Patients With Hypertension to a Digital Remote Blood Pressure Monitoring Program: Mixed Methods Study

Long-term control of hypertension can be achieved through proven interventions including regular blood pressure (BP) monitoring [2]. Accurate BP measurements in the office can be a challenge, particularly if the patient has white coat syndrome [3]. Digital technology including digital remote blood pressure monitoring (RBPM) allows health care to conduct remote monitoring for many chronic diseases [4,5].

Jennifer J Wu, Ross Graham, Julie Çelebi, Kevin Fraser, Geneen T Gin, Laurel Dang, Esmatullah Hatamy, Amanda Walker, Courtney Barbato, Ottar Lunde, Lisa Coles, Parag Agnihotri, Cassandra Morn, Ming Tai-Seale

J Med Internet Res 2025;27:e64933

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HIV Incidence and Associated Risk Factors Among Young Men Who Have Sex With Men in Tianjin, China: Retrospective Cohort Study

HIV Incidence and Associated Risk Factors Among Young Men Who Have Sex With Men in Tianjin, China: Retrospective Cohort Study

Our study is the first long-term cohort study to assess the incidence of HIV and its associated factors among YMSM in Tianjin. The HIV incidence identified in this study was similar to the incidence among MSM under 24 years old (2.63/100 PYs) in Shanghai, published in 2019 [17]. This study found that the incidence of HIV among YMSM in Tianjin showed a stable trend from 2017 to 2022 and was maintained at an elevated level.

Yan Guo, Hui Gong, Xiangyu Yan, Xinying Zhang, Tielin Ning, Zhongquan Liu, Long Li, Jie Yang, Liu Li, Changxu Ma, Zhuang Cui, Maohe Yu

JMIR Public Health Surveill 2025;11:e66487

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Article has an altmetric score of 1