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Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

This would occur in the intervention arm only, but there will not be any syphilis testing done by systems navigators (they only collect urine for N. gonorrhea and C. trachomatis). All participants will complete study staff-administered surveys using validated scales whenever possible, enabling exploration of predictors of Pr EP persistence and informing targeted objectives and strategies to enhance systems navigation and counseling interventions.

Sarah E Rutstein, Laura Limarzi-Klyn, Jane S Chen, Yaw O Agyei, Shahnaz Ahmed, Ian Bell, Myron Cohen, Jessica M Fogel, Vivian Go, Dan Haines, Erica L Hamilton, Irving F Hoffman, Mina C Hosseinipour, Mark A Marzinke, William C Miller, Mathews Mukatipa, Julie Pulerwitz, Hans M L Spiegel, Ting Ye, Mitch Matoga

JMIR Res Protoc 2025;14:e72981

Feasibility and Usability of a Web-Based Peer Support Network for Care Partners of People With Serious Illness (ConnectShareCare): Observational Study

Feasibility and Usability of a Web-Based Peer Support Network for Care Partners of People With Serious Illness (ConnectShareCare): Observational Study

We used statistical process control c Charts [18] to identify changes in enrollment and engagement over time. We used descriptive statistics to summarize categorical information from survey responses. We conducted descriptive statistics with SPSS (version 28; IBM Corp). Subgroup analyses were not conducted due to the small sample size. Missing data were excluded on an analysis-by-analysis basis.

Aricca D Van Citters, Megan M Holthoff, Colleen Young, Sarah M Eck, Amelia M Cullinan, Stephanie Carney, Elizabeth A O'Donnell, Joel R King, Malavika Govindan, David Gustafson, Stephanie C Tomlin, Anne B Holmes, Ann D Bradley, Brant J Oliver, Matthew M Wilson, Eugene C Nelson, Amber E Barnato, Kathryn B Kirkland

JMIR Form Res 2025;9:e70206