TY - JOUR AU - Takagi, Soshi AU - Watari, Takashi AU - Erabi, Ayano AU - Sakaguchi, Kota PY - 2023 DA - 2023/6/29 TI - Performance of GPT-3.5 and GPT-4 on the Japanese Medical Licensing Examination: Comparison Study JO - JMIR Med Educ SP - e48002 VL - 9 KW - ChatGPT KW - Chat Generative Pre-trained Transformer KW - GPT-4 KW - Generative Pre-trained Transformer 4 KW - artificial intelligence KW - AI KW - medical education KW - Japanese Medical Licensing Examination KW - medical licensing KW - clinical support KW - learning model AB - Background: The competence of ChatGPT (Chat Generative Pre-Trained Transformer) in non-English languages is not well studied. Objective: This study compared the performances of GPT-3.5 (Generative Pre-trained Transformer) and GPT-4 on the Japanese Medical Licensing Examination (JMLE) to evaluate the reliability of these models for clinical reasoning and medical knowledge in non-English languages. Methods: This study used the default mode of ChatGPT, which is based on GPT-3.5; the GPT-4 model of ChatGPT Plus; and the 117th JMLE in 2023. A total of 254 questions were included in the final analysis, which were categorized into 3 types, namely general, clinical, and clinical sentence questions. Results: The results indicated that GPT-4 outperformed GPT-3.5 in terms of accuracy, particularly for general, clinical, and clinical sentence questions. GPT-4 also performed better on difficult questions and specific disease questions. Furthermore, GPT-4 achieved the passing criteria for the JMLE, indicating its reliability for clinical reasoning and medical knowledge in non-English languages. Conclusions: GPT-4 could become a valuable tool for medical education and clinical support in non–English-speaking regions, such as Japan. SN - 2369-3762 UR - https://mededu.jmir.org/2023/1/e48002 UR - https://doi.org/10.2196/48002 UR - http://www.ncbi.nlm.nih.gov/pubmed/37384388 DO - 10.2196/48002 ID - info:doi/10.2196/48002 ER -