TY - JOUR AU - Faghihzadeh, Elham AU - Eghtesad, Ali AU - Fawad, Muhammad AU - Xu, Xiaolin PY - 2025 DA - 2025/5/15 TI - Exploring Connections Between Mental Health, Burnout, and Academic Factors Among Medical Students at an Iranian University: Cross-Sectional Questionnaire Study JO - JMIR Med Educ SP - e58008 VL - 11 KW - emotional exhaustion KW - exhaustion KW - cynicism KW - academic efficacy KW - burnout KW - physician burnout KW - mental health KW - mental illness KW - mental disease KW - mental disorder KW - medical education KW - medical knowledge KW - medical training KW - medical student KW - resident physician KW - resident doctor KW - residency KW - residency training AB - Background: Medical students face high levels of burnout and mental health issues during training. Understanding associated factors can inform supportive interventions. Objective: This study aimed to examine burnout, psychological well-being, and related demographics among Iranian medical students. Methods: A cross-sectional survey was conducted among 131 medical students at an Iranian University. The instruments used included the Maslach Burnout Inventory-Student Survey and the Symptom Checklist-90-Revised. Descriptive statistics, multivariate regression, and tests for group differences were used to analyze the data. Results: The MBI-SS subscale scores indicated moderate emotional exhaustion, mean 15.00 (SD 7.08) and academic efficacy, mean 14.98 (SD 6.29), with lower cynicism, mean 10.85 (SD 5.89). The most commonly reported mental health issues were depression and obsessive-compulsive disorder. Poor psychological well-being was associated with higher overall burnout, but no significant gender differences were found. Burnout levels varied by academic year across all Maslach Burnout Inventory-Student Survey domains. Conclusions: Despite their health education, medical students in this study reported significant burnout and mental health distress, with strong associations between the two. These issues may impact student retention and post-graduation practice plans. Supporting well-being during training is critical for positive student and physician outcomes. SN - 2369-3762 UR - https://mededu.jmir.org/2025/1/e58008 UR - https://doi.org/10.2196/58008 DO - 10.2196/58008 ID - info:doi/10.2196/58008 ER -