%0 Journal Article %@ 2369-3762 %I JMIR Publications %V 9 %N %P e48586 %T The Impact of Web-Based Continuing Medical Education Using Patient Simulation on Real-World Treatment Selection in Type 2 Diabetes: Retrospective Case-Control Analysis %A Lucero,Katie Stringer %A Larkin,Amy %A Zakharkin,Stanislav %A Wysham,Carol %A Anderson,John %+ Medscape, LLC, 395 Hudson St, New York, NY, 10014, United States, 1 212 301 6782, klucero@webmd.net %K continuing medical education %K virtual patient simulation %K real-world evidence %K evaluation %K outcomes %K diabetes education %K medical education %K type 2 diabetes %K web-based learning %K web-based education %D 2023 %7 29.8.2023 %9 Original Paper %J JMIR Med Educ %G English %X Background: Despite guidelines recommending the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in certain patients with type 2 diabetes (T2D), they are not being prescribed for many of these patients. Web-based continuing medical education (CME) patient simulations have been used to identify clinicians’ practice gaps and improve clinical decision-making as measured within a simulation, but the impact of this format on real-world treatment has not been researched. Objective: This study aimed to evaluate the effect of a simulation-based CME intervention on real-world use of GLP-1 RAs by endocrinologists and primary care physicians. Methods: Two evaluation phases of the CME simulation were conducted: phase I, the CME simulation phase, was a paired, pre-post study of 435 physician learners in the United States; and phase II, the real-world phase, was a retrospective, matched case-control study of 157 of the 435 physicians who had claims data available for the study period. Results: Phase I CME results showed a 29 percentage point increase in correct decisions from pre- to postfeedback (178/435, 40.9% to 304/435, 69.9%; P<.001) in selecting treatment that addresses both glycemic control and cardiovascular event protection. Phase II results showed that 39 of 157 (24.8%) physicians in the intervention group increased use of GLP-1 RAs, compared to 20 of 157 (12.7%) in the comparison group. Being in the intervention group predicted GLP-1 RA use after education (odds ratio 4.49; 95% CI 1.45-13.97; P=.001). Conclusions: A web-based CME simulation focused on secondary prevention of cardiovascular events in a patient with T2D was associated with increased use of evidence-based treatment selection in the real world. %M 37642994 %R 10.2196/48586 %U https://mededu.jmir.org/2023/1/e48586 %U https://doi.org/10.2196/48586 %U http://www.ncbi.nlm.nih.gov/pubmed/37642994