A self-reported web-based questionnaire survey that included 10 questions was introduced to a group of medical school graduates through Facebook and WhatsApp (Figure 1, Table 1). All respondents were Cairo University Faculty of Medicine medical graduates, and they specialized in different clinical and academic departments. The survey asked about the respondents’ interest in research, possible applications of their research project in the medical field, reasons for the delay in completion (ie, the delay in final publication), and suggested reasons for journal rejection. The research success of the participants was measured by the completion rate of publishing any number of papers, even one paper, as well as their state of authorship of the paper (first or other author). Out of 150 recipients, 130 responded to the survey in the period from June 15-30, 2020. Data from the survey were exported to an Excel spreadsheet (Microsoft Corporation) and analyzed using GraphPad Prism, version 8.0.0, for Windows (GraphPad Software Inc). We considered two-tailed P values <.05 to be statistically significant for all differences. Descriptive analysis was performed regarding age, gender, and marital status. The Mann-Whitney U test was applied as a nonparametric test to identify significant differences for each of the variables under study and how they relate to each other, such as whether the rates of completion and publishing differ according to the graduate’s marital status or the availability of a helpful mentor.

All participants were consented to share their views and test results in the survey. All data used were anonymized and encrypted to comply with all research ethics. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Postgraduate medical education is constantly changing on a large scientific scale. Very large data sets and technological advances have begun to demonstrate different clinical applications. Therefore, a proper methodology to investigate the lack of interest in research among medical graduates is needed. Research is a dynamic process that includes creating a research idea, followed by scientific writing and publishing. Some factors impede this process at any step; therefore, we attempted to summarize these factors as well as possible.

In this study, 72.3% of the participants reported that they did not have a good supervising mentor, and they considered that to be a cause of delay in publishing their research. Mentorship is a responsibility that requires diligent availability of time and scientific resources, and it is a crucial item in research implementation [2]. In developing countries, mentors are usually busy focusing on clinical activities such as performing surgeries and attending outpatient clinics, and they do not have sufficient time for research mentoring [2]. The significance of providing proper active mentorship at academic and clinical institutions is receiving increasing attention worldwide [3].

We observed that 56.2% of the respondents to our survey were not interested in research. Therefore, it is pivotal to delineate the factors that eventually lead to this lack of interest. One remarkable issue that may decrease interest in research is the absence of an interesting project idea. Scientific idea design is an essential step in the process of research accomplishment. Lack of novelty and outdated ideas are a major cause of manuscript rejection; in this study, this represents the cause for rejection of 39.2% of the participants (51/130), as analyzed above. The research question plays a valuable role in the overall research process and should be fashioned meticulously [4].

It is noteworthy that most research is costly and requires funding. Lack of adequate funding, especially in developing countries, is an obstacle that disrupts the process of publishing. Resource allocation for research is a critical point that should be well considered. In this study, 78.5% of medical graduates did not have any funding for their research projects. We found a strong relationship between the scarcity of funds and the noncompletion of research (P=.04). Financial aid for researchers at academic institutions should be assigned properly, as this is considered to be an investment in proper patient care in the future [5].

One of the factors that affected the completion rate was the social restrictions for married medical graduates. Of the 130 respondents, 76 (58.5%) were married, and we found that a significant number of married researchers did not complete or publish their work compared to unmarried researchers, as indicated by the P value of .002. Family commitments and social relations are considered to be a source of stress for some medical graduates, specifically at the beginning of their careers. The academic performance of married researchers will certainly improve if both partners are cooperative, are helpful, and support each other [6].

The rate of rejection of manuscripts submitted to different medical journals is higher in developing countries than in Europe and North America [7]. We attempted to explicate the causes of manuscript rejection and review the suggested reasons among a group of postgraduate medical researchers. We found that 51 of the 130 persons involved in the study (39.2%) suggested that their work was rejected mainly because the idea was extensively discussed in the literature and did not provide any new scientific or statistical data to the reader. Therefore, a careful, systematic selection of the idea of the research project should be emphasized. The next suggested reason is the lack of value of the research idea; 16% of the participating physicians reported that their research projects were not beneficial. Plagiarism was the cause of 13.8% of the rejected work in this study. Plagiarism is a serious ethical issue that is considered to be misconduct by most research institutions. It is important for research program directors to arrange workshops and lectures to teach young researchers how to avoid plagiarism. The Indian Journal of Dermatology prohibited a group of Tunisian researchers from publishing in the journal due to the submission of a plagiarized article [8]. Proper training and educational courses about scientific writing should be presented to medical students and graduates to improve their research skills, which will help them to accomplish their research projects for the sake of improving patient care.

Online questionnaire surveys are subjective and liable to bias from some respondents. The sample size is small, so it cannot be generalized; moreover, the study relates to only one institution in Egypt, the Cairo University Faculty of Medicine, and thus it does not represent all medical graduates. Generalization of the study requires a multi-institution approach.

Factors affecting the pursuit of research by medical graduates are clear to the scientific community. Dedicated efforts and organized plans should be assigned to help medical graduates in developing countries to improve their research skills.